3,5-Bis(aminomethyl)pyridine - Names and Identifiers
3,5-Bis(aminomethyl)pyridine - Physico-chemical Properties
Molecular Formula | C7H11N3
|
Molar Mass | 137.18 |
Density | 1.118±0.06 g/cm3(Predicted) |
Boling Point | 301.2±32.0 °C(Predicted) |
pKa | 8.63±0.29(Predicted) |
Refractive Index | 1.587 |
3,5-Bis(aminomethyl)pyridine - Introduction
3,5-Bis(aminomethyl)pyridine(3,5-Bis(aminomethyl)pyridine) is an organic compound with the chemical formula C8H12N2. The following is a description of the nature, use, preparation and safety information of the substance:
Nature:
-Appearance: 3,5-Bis(aminomethyl)pyridine is a colorless to pale yellow liquid.
-Solubility: It can be dissolved in common organic solvents, such as ethanol, ether and dimethyl sulfoxide.
-Melting point and boiling point: The melting point of 3,5-Bis(aminomethyl)pyridine is about 28-29°C, and the boiling point is about 220-222°C.
- pH: Its pH in water is usually neutral.
Use:
3,5-Bis(aminomethyl)pyridine is basic, so it is often used as a ligand in organic synthesis to catalyze reactions and prepare metal complexes. It can be used in organic synthesis to catalyze the addition reaction of aldehydes and ketones, Michael addition reaction, etc. In addition, it can also be used as a precursor for surfactants in the fields of coatings, adhesives and lubricants.
Method:
3,5-Bis(aminomethyl)pyridine is generally carried out by reacting 2,6-lutidine using sodium hypochlorite (NaOCl) as an oxidizing agent to obtain an intermediate 2,6-lutidine -4,5-dione, and then generating 3,5-Bis(aminomethyl)pyridine by reduction with formaldehyde (HCHO).
Safety Information:
- 3,5-Bis(aminomethyl) is pyridine irritating and should be avoided in contact with skin and eyes. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation.
-It should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
-When using or handling this substance, you need to follow local health and safety regulations, avoid inhaling dust or solutions, and avoid mixing with other chemicals. In the event of an accident, appropriate emergency measures should be taken immediately and professional medical advice should be sought.
Last Update:2024-04-10 22:29:15