3-(2,4-Difluorophenoxy)azetidine hydrochloride
3-(2,4-Difluorophenoxy)azetidine hydrochloride
CAS: 1241675-84-2
Molecular Formula: C9H10ClF2NO
3-(2,4-Difluorophenoxy)azetidine hydrochloride - Names and Identifiers
| Name | 3-(2,4-Difluorophenoxy)azetidine hydrochloride |
| Synonyms | 3-(2,4-Difluorophenoxy)azetidine hydrochloride |
| CAS | 1241675-84-2 |
3-(2,4-Difluorophenoxy)azetidine hydrochloride - Physico-chemical Properties
| Molecular Formula | C9H10ClF2NO |
| Molar Mass | 221.6316064 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD16872040 |
3-(2,4-Difluorophenoxy)azetidine hydrochloride - Risk and Safety
| Hazard Class | IRRITANT |
3-(2,4-Difluorophenoxy)azetidine hydrochloride - Introduction
3-(2,4-Difluorophenoxy)azetidine hydrochloride is an organic compound with a chemical formula of C8H9ClF2NO and a molecular weight of 205.61g/mol. It is a solid crystal, soluble in water and some organic solvents such as alcohols and ethers.
3-(2,4-Difluorophenoxy)azetidine hydrochloride is often used as an intermediate in the pharmaceutical field. It has a broad spectrum of antibacterial activity, especially for beta-lactamase-resistant bacteria have good antibacterial activity. Therefore, in the pharmaceutical process, it can be used to synthesize new antibacterial drugs, such as antibiotics. In addition, it can be used to study and develop structure-activity correlations of antibiotics, as well as studies of medicinal chemistry and drug metabolism.
The preparation of 3-(2,4-Difluorophenoxy)azetidine hydrochloride is relatively simple. A typical preparation method is to react 2,4-difluorophenol with chlorogenic reagents, perform a ring reaction under alkaline conditions to obtain the desired product, and finally add hydrochloric acid to form a hydrochloride.
Regarding safety information, 3-(2,4-Difluorophenoxy)azetidine hydrochloride is stable under general working conditions, but may decompose at high temperatures or in contact with strong acids. Therefore, high temperature and strong acidic conditions should be avoided during use. In addition, because it is an organic compound, it may have certain toxicity and irritation, so appropriate protective measures such as gloves and goggles should be worn during operation.
3-(2,4-Difluorophenoxy)azetidine hydrochloride is often used as an intermediate in the pharmaceutical field. It has a broad spectrum of antibacterial activity, especially for beta-lactamase-resistant bacteria have good antibacterial activity. Therefore, in the pharmaceutical process, it can be used to synthesize new antibacterial drugs, such as antibiotics. In addition, it can be used to study and develop structure-activity correlations of antibiotics, as well as studies of medicinal chemistry and drug metabolism.
The preparation of 3-(2,4-Difluorophenoxy)azetidine hydrochloride is relatively simple. A typical preparation method is to react 2,4-difluorophenol with chlorogenic reagents, perform a ring reaction under alkaline conditions to obtain the desired product, and finally add hydrochloric acid to form a hydrochloride.
Regarding safety information, 3-(2,4-Difluorophenoxy)azetidine hydrochloride is stable under general working conditions, but may decompose at high temperatures or in contact with strong acids. Therefore, high temperature and strong acidic conditions should be avoided during use. In addition, because it is an organic compound, it may have certain toxicity and irritation, so appropriate protective measures such as gloves and goggles should be worn during operation.
Last Update：2024-04-09 21:04:16
