3-(TRIFLUOROMETHYL)PYRROLIDINE

3-(TRIFLUOROMETHYL)PYRROLIDINE - Names and Identifiers

Name	3-(trifluoromethyl)pyrrolidine
Synonyms	LogP 3-(trifluoromethyl)pyrrolidine 3-(TRIFLUOROMETHYL)PYRROLIDINE Pyrrolidine, 3-(trifluoromethyl)-
CAS	644970-41-2
InChI	InChI=1/C5H8F3N/c6-5(7,8)4-1-2-9-3-4/h4,9H,1-3H2

3-(TRIFLUOROMETHYL)PYRROLIDINE - Physico-chemical Properties

Molecular Formula	C5H8F3N
Molar Mass	139.12
Density	1.180
Boling Point	89℃
Flash Point	8℃
Vapor Presure	60.3mmHg at 25°C
Storage Condition	2-8℃
Refractive Index	1.368

3-(TRIFLUOROMETHYL)PYRROLIDINE - Introduction

3-(trifluoromethyl)pyrrolidine is an organic compound with the chemical formula C5H7NF3 · HCl. It has the following properties:

1. Appearance: a white solid
2. melting point: about 105-108 ℃
3. Boiling point: about 156-157 ℃
4. Solubility: Soluble in water and some organic solvents, such as ethanol and ether.
The main uses of
3-(trifluoromethyl)pyrrolidine are:

1. As a reagent in organic synthesis: commonly used in the synthesis of a variety of organic compounds, such as precursors for synthetic drugs or pesticides.
2. for catalytic reaction: can be used as a catalyst to promote certain chemical reactions.
3. used in the field of medicine: potential use as drug intermediates.

A common method for preparing 3-(trifluoromethyl)pyrrolidine is through the reaction of pyrrole and 4-trifluoromethylacetophenone. In the preparation process, attention should be paid to the reaction conditions and operation mode to ensure the high selectivity and yield of the reaction.

Safety concerns when using and handling 3-(trifluoromethyl)pyrrolidine:

1. avoid contact with skin, eyes and respiratory tract: can cause irritation and pain.
2. avoid inhalation of dust or steam: in the process of operation to maintain good ventilation conditions.
3. If contact occurs, immediately flush the affected area with plenty of water and seek medical help.
4. During use and storage, care should be taken to avoid fire and high temperature.
5. It is recommended to wear appropriate personal protective equipment during operation, such as lab gloves, safety glasses and protective clothing.

Last Update：2024-04-09 21:21:28