3-(4-CHLORO-BENZYL)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER
1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID
CAS: 174606-16-7
Molecular Formula: C18H24ClNO4
3-(4-CHLORO-BENZYL)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER - Names and Identifiers
3-(4-CHLORO-BENZYL)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER - Physico-chemical Properties
| Molecular Formula | C18H24ClNO4 |
| Molar Mass | 353.84 |
| Storage Condition | Sealed in dry,Room Temperature |
3-(4-CHLORO-BENZYL)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Hazard Class | IRRITANT |
3-(4-CHLORO-BENZYL)-PIPERIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER - Introduction
1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID is an organic compound with the following chemical structure:
It has the following properties:
1. Appearance: white or white crystalline solid.
2. Molecular formula: C18H22ClNO4.
3. Molecular weight: 357.82g/mol.
4. Melting point: About 60-65 ° C.
1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID is commonly used as a protecting group in organic synthesis. Its Main uses include:
1. In synthetic chemistry, it can be used as a nitrogen protecting group and a carboxyl protecting group in the reaction of protecting amino compounds and carboxylic acid compounds to control the selectivity of the reaction and avoid unnecessary side reactions.
2. It can also be used to synthesize drug intermediates, such as piperazine antipsychotic drugs, anticancer drugs, etc.
The method for preparing 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID is as follows:
First, 1-piperidinecarboxylic acid and 4-chlorobenzyl alcohol are reacted to produce 4-chlorobenzyl-1-piperidinecarboxylic acid. This intermediate is then esterified with reagents such as Bu3P and CO2 to give 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID.
Note the following safety information when using and handling 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID:
1. The compound is an organic chemical with certain toxicity, and appropriate personal protective measures should be taken.
2. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical attention.
3. Avoid inhaling its powder or gas. It is recommended to operate in a well-ventilated place.
4. Please keep and store properly, away from fire and heat sources.
5. The compound is an organic synthesis reagent, which is limited to scientific research and industrial use, and is prohibited from direct application to humans or animals.
It has the following properties:
1. Appearance: white or white crystalline solid.
2. Molecular formula: C18H22ClNO4.
3. Molecular weight: 357.82g/mol.
4. Melting point: About 60-65 ° C.
1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID is commonly used as a protecting group in organic synthesis. Its Main uses include:
1. In synthetic chemistry, it can be used as a nitrogen protecting group and a carboxyl protecting group in the reaction of protecting amino compounds and carboxylic acid compounds to control the selectivity of the reaction and avoid unnecessary side reactions.
2. It can also be used to synthesize drug intermediates, such as piperazine antipsychotic drugs, anticancer drugs, etc.
The method for preparing 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID is as follows:
First, 1-piperidinecarboxylic acid and 4-chlorobenzyl alcohol are reacted to produce 4-chlorobenzyl-1-piperidinecarboxylic acid. This intermediate is then esterified with reagents such as Bu3P and CO2 to give 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID.
Note the following safety information when using and handling 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID:
1. The compound is an organic chemical with certain toxicity, and appropriate personal protective measures should be taken.
2. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical attention.
3. Avoid inhaling its powder or gas. It is recommended to operate in a well-ventilated place.
4. Please keep and store properly, away from fire and heat sources.
5. The compound is an organic synthesis reagent, which is limited to scientific research and industrial use, and is prohibited from direct application to humans or animals.
Last Update：2024-04-09 21:21:28
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Product Name: 1-[(TERT-BUTYL)OXYCARBONYL]-3-(4-CHLOROBENZYL)PIPERIDINE-3-CARBOXYLIC ACID Visit Supplier Webpage Request for quotation
CAS: 174606-16-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 174606-16-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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