3-(Bromomethyl)piperidine, N-BOC protected
1-BOC-3-BROMOMETHYLPIPERIDINE
CAS: 193629-39-9
Molecular Formula: C11H20BrNO2
3-(Bromomethyl)piperidine, N-BOC protected - Names and Identifiers
3-(Bromomethyl)piperidine, N-BOC protected - Physico-chemical Properties
| Molecular Formula | C11H20BrNO2 |
| Molar Mass | 278.19 |
| Density | 1.270 |
| Boling Point | 318.3±15.0 °C(Predicted) |
| Flash Point | 146.3°C |
| Vapor Presure | 0.000363mmHg at 25°C |
| pKa | -2.03±0.40(Predicted) |
| Storage Condition | Sealed in dry,Store in freezer, under -20°C |
| Refractive Index | 1.495 |
3-(Bromomethyl)piperidine, N-BOC protected - Risk and Safety
| Risk Codes | 36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
3-(Bromomethyl)piperidine, N-BOC protected - Introduction
It is an organic compound with the chemical formula C12H19BrNO2.
Nature:
It is a white solid with a low melting and boiling point. It is a derivative of Bromo piperidine, with strong alkaline. This compound is soluble at room temperature in some organic solvents, such as dimethyl sulfoxide and methylene chloride.
Use:
is a reagent commonly used in organic synthesis. It is often used in the synthesis of other corresponding compounds, especially in the field of medicine as a prodrug. In addition, it can also be used as a catalyst and an intermediate.
Method:
can be obtained by reacting chloromethyl ethyl ether with piperidine and then bromination reaction. Finally, the target compound is obtained by reaction with Boc (tert-butoxycarbonyl) acid. The reaction process needs to be carried out under the protection of inert gas.
Safety Information:
It has low toxicity under general conditions. However, as an organic synthesis reagent, it still needs to be handled under suitable laboratory conditions, avoiding contact with skin and inhalation of gas or dust. During use, you should pay attention to good ventilation and wear appropriate personal protective equipment, such as gloves and glasses.
Generally speaking, it is a commonly used organic compound and has important application value, but it is necessary to pay attention to safe operation during use.
Nature:
It is a white solid with a low melting and boiling point. It is a derivative of Bromo piperidine, with strong alkaline. This compound is soluble at room temperature in some organic solvents, such as dimethyl sulfoxide and methylene chloride.
Use:
is a reagent commonly used in organic synthesis. It is often used in the synthesis of other corresponding compounds, especially in the field of medicine as a prodrug. In addition, it can also be used as a catalyst and an intermediate.
Method:
can be obtained by reacting chloromethyl ethyl ether with piperidine and then bromination reaction. Finally, the target compound is obtained by reaction with Boc (tert-butoxycarbonyl) acid. The reaction process needs to be carried out under the protection of inert gas.
Safety Information:
It has low toxicity under general conditions. However, as an organic synthesis reagent, it still needs to be handled under suitable laboratory conditions, avoiding contact with skin and inhalation of gas or dust. During use, you should pay attention to good ventilation and wear appropriate personal protective equipment, such as gloves and glasses.
Generally speaking, it is a commonly used organic compound and has important application value, but it is necessary to pay attention to safe operation during use.
Last Update：2024-04-09 21:00:56
