3-(N-BOC-N-甲基氨基)吡咯烷

3-(N-BOC-N-甲基氨基)吡咯烷 - Names and Identifiers

Name	3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine
Synonyms	3-(N-BOC-N-METHYLAMINO)PYRROLIDINE 3-(N-METHYL-N-BOC-AMINO)PYRROLIDINE (S)-3-(N-BOCMETHYLAMINO)PYRROLIDINE (S)-3-(N-Bocmethylamino)Pyrrolidine -tert-Butyl methyl(pyrrolidin-3-yl) tert-butyl methyl(pyrrolidin-3-yl)carbamate tert-butyl methyl[(3S)-pyrrolidin-3-yl]carbamate (3S)-3-Amino-N-methylpyrrolidine, N-BOC protected 3-(N-METHYL-N-TERT-BUTOXYCARBONYLAMINO)PYRROLIDINE 3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine (S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]pyrrolidine (3S)-3-[N-(tert-Butoxycarbonyl)-N-methylamino]pyrrolidine
CAS	169750-01-0
InChI	InChI=1/C10H20N2O2/c1-10(2,3)14-9(13)7-12-8-4-5-11-6-8/h8,11-12H,4-7H2,1-3H3/t8-/m0/s1

3-(N-BOC-N-甲基氨基)吡咯烷 - Physico-chemical Properties

Molecular Formula	C10H20N2O2
Molar Mass	200.28
Density	1.03
Boling Point	268℃
Flash Point	116℃
pKa	9.85±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.48

3-(N-BOC-N-甲基氨基)吡咯烷 - Introduction

3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine is an organic compound with the formula C11H16N2O2. The following is a description of its nature, use, preparation and safety information:

Properties: 3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine is a white crystalline solid with good solubility and can be dissolved in some organic solvents. It is a chiral compound, optically active, capable of optical rotation.

Uses: 3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine is widely used in the field of organic synthesis. It is often used as a chiral reagent, a chiral intermediate or a chiral ligand. Its applications include asymmetric catalysis, chiral controlled reactions, drug synthesis, etc. By introducing a BOC protecting group and a methylaminopyrrole group, the compounds can be made stereoselective in the reaction.

Preparation Method: The preparation of 3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine can be achieved by various methods. A common method is to use acetylacetone and (N-BOC) methylaminopyrrolidone in the presence of sodium hydroxide to give the corresponding 3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine.

Safety information: 3-(N-Tert-Butoxycarbonyl-N-Methylamino)Pyrrolidine is less toxic and dangerous, but it still needs to be used with care. Avoid contact with strong oxidants, strong acids and strong bases during handling and storage. Wear appropriate personal protective equipment, such as lab gloves and protective glasses. For inadvertent contact with skin or eyes, rinse immediately with plenty of water. Follow local regulations when disposing of waste.

Last Update：2024-04-09 02:00:43