3-(T-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID

3-(T-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID - Names and Identifiers

Name	3-(tert-Butyldimethylsiloxy)benzeneboronic acid
Synonyms	3-(tert-Butyldimethylsilyloxy)phenylboronic 3-(T-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID 3-(T-BUTYL DIMETHYLSILOXY) PHENYL BORONIC ACID 3-(tert-Butyldimethylsilyoxy)phenylboronic acid 3-(tert-Butyldimethylsiloxy)benzeneboronic acid 3-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID 3-(TERT-BUTYL DIMETHYLSILOXY) PHENYL BORONIC ACID (3-{[tert-Butyl(dimethyl)silyl]oxy}phenyl)boronic acid 3-(tert-Butyldimethylsilyloxy)phenylboronic acid, tech. grade boronic acid, B-[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-
CAS	261621-12-9
InChI	InChI=1/C12H21BO3Si/c1-12(2,3)17(4,5)16-11-8-6-7-10(9-11)13(14)15/h6-9,14-15H,1-5H3

3-(T-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID - Physico-chemical Properties

Molecular Formula	C12H21BO3Si
Molar Mass	252.19
Density	1.01±0.1 g/cm3(Predicted)
Melting Point	86-91°C(lit.)
Boling Point	330.3±44.0 °C(Predicted)
Flash Point	153.5°C
Solubility	soluble in Methanol
Vapor Presure	6.74E-05mmHg at 25°C
Appearance	Powder
Color	Off-white
pKa	8.11±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.489
MDL	MFCD03701505

3-(T-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves.
WGK Germany	3
HS Code	29319090
Hazard Class	IRRITANT

3-(T-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID - Introduction

3-(tert-Butyldimethylsiloxy)benzeneboronic acid is an organic boron compound with the chemical formula C10H17BCO3Si.

Nature:
-Appearance is solid, soluble in organic solvents such as chloroform, dimethylformamide, etc.
-It is an acidic substance that can undergo a substitution reaction with electrophiles.
-It has good thermal stability and solubility, and can be widely used in organic synthesis reactions.

Use:
- 3-(tert-Butyldimethylsiloxy)benzeneboronic acid can be used as an important reagent in organic synthesis and participate in the synthesis of important aryl borate esters such as Suzuki coupling reaction.
-It can be used to prepare molecules with biological activity, such as drugs, pesticides, photoelectric materials, etc.

Method:
- 3-(tert-Butyldimethylsiloxy)benzeneboronic acid is generally prepared by reacting p-chlorobenzene with tert-butyldimethylfluorosilicone under alkaline conditions, the 3-(tert-Butyldimethylsiloxy)benzeneboronic acid is then formed with tributylboron hydrochloride.

Safety Information:
- 3-(tert-Butyldimethylsiloxy)benzeneboronic acid has no obvious danger under normal use conditions.
-During operation, direct contact with skin and eyes should be avoided.
-In case of contact, rinse immediately with plenty of water and seek medical assistance.
-When storing, it should be kept in a dry, cool, well-ventilated place, and stored in isolation from oxidants, strong acids and other substances.

Last Update：2024-04-09 02:00:44