3-(thiophen-2-yl)propanoic acid

3-(thiophen-2-yl)propanoic acid - Names and Identifiers

Name	3-(2-Thienyl)propanoic acid
Synonyms	AKOS B029955 2-thiophenepropionic acid 2-Thiophenepropanoic acid 3-thiophen-2-ylpropanoate 3-thien-2-ylpropanoic acid 2-Thiophenepropanoic acid. 3-(2-Thienyl)Propionic Acid 3-(2-THIENYL)PROPIONIC ACID 3-(2-Thienyl)propanoic acid 3-(2-THIENYL)PROPANOIC ACID 3-(2-THIENYL)PROPOINIC ACID 3-THIOPHEN-2-YL-PROPIONIC ACID 3-(thiophen-2-yl)propanoic acid 1-(3,4-dimethoxyphenyl)-3-(diphenylmethyl)urea
CAS	5928-51-8
InChI	InChI=1/C7H5BrN2/c8-6-2-1-5-4-9-10-7(5)3-6/h1-4H,(H,9,10)

3-(thiophen-2-yl)propanoic acid - Physico-chemical Properties

Molecular Formula	C7H8O2S
Molar Mass	156.2
Density	1.2474 (rough estimate)
Melting Point	46-49°C(lit.)
Boling Point	250.45°C (rough estimate)
Flash Point	>230°F
Vapor Presure	0mmHg at 25°C
Appearance	Crystals or Needles
Color	White to beige
pKa	4.47±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.5460 (estimate)

3-(thiophen-2-yl)propanoic acid - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3261 8/PG 2
WGK Germany	3
HS Code	29309099

3-(thiophen-2-yl)propanoic acid - Introduction

3-(2-Thienyl)propanoic acid is an organic compound whose chemical formula is C8H8O2S. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White to light yellow crystalline powder.
-Solubility: Soluble in many organic solvents, such as ethanol, dimethylformamide and dichloromethane.

Use:
- 3-(2-Thienyl)propanoic acid is an important organic synthesis intermediate, widely used in pharmaceutical synthesis, materials science and organic electronics.
-In drug synthesis, it can be used to synthesize active natural products, drugs and enzyme activity regulators, etc.
-In materials science, it can be used to synthesize polymers with specific properties for the preparation of optoelectronic materials, catalysts and photosensitive materials.
-In the field of organic electronics, it can be used to prepare organic thin films with semiconductor properties for the preparation of organic optoelectronic devices.

Preparation Method:
- 3-(2-Thienyl)propanoic acid can be prepared by the reaction of thiophene with acrylic acid. The specific preparation method is as follows:
1. Reactant preparation: Thiophene and acrylic acid are respectively dissolved in an appropriate organic solvent.
2. Reaction: The reactants are mixed and heated for reaction. Typically, the product is obtained after reaction at a temperature under an inert atmosphere for several hours to several days.
3. product purification: the reaction mixture is separated and purified by crystallization, solvent extraction and other methods to obtain a pure product.

Safety Information: The specific toxicity and safe handling of
- 3-(2-Thienyl)propanoic acid have not been reported in detail. But as an organic compound, it can cause irritation and damage to the skin, eyes and respiratory system. Therefore, when in contact with it, be sure to take appropriate protective measures, such as wearing chemical goggles, gloves and protective clothing. At the same time, should avoid inhalation of its dust or solution, avoid swallowing. In case of accidental contact, rinse immediately with plenty of water and seek medical assistance. During use or storage, the relevant chemical safety procedures should be followed to ensure safe use.

Last Update：2024-04-09 21:11:58