3-ALPHA,6-ALPHA,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - Names and Identifiers
Name | HYOCHOLIC ACID
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Synonyms | HYOCHOLIC ACID GAMMA MURICHOLIC LAMBDA-MURICHOLIC ACID 5B-CHOLAN-24-OIC ACID-3A,6A,7A-TRIOL 3A,6A-7A-TRIHYDROXY-5B-CHOLAN-24-OIC ACID 5-BETA-CHOLAN-24-OIC ACID-3-ALPHA,6-ALPHA,7-ALPHA-TRIOL 3-ALPHA,6-ALPHA,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID 3,6,7-trihydroxy-,(3alpha,5beta,6alpha,7alpha)-cholan-24-oicaci
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CAS | 547-75-1
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EINECS | 208-935-8 |
3-ALPHA,6-ALPHA,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - Physico-chemical Properties
Molecular Formula | C24H40O5
|
Molar Mass | 408.57 |
Density | 1.184±0.06 g/cm3(Predicted) |
Melting Point | 162 °C |
Boling Point | 565.7±40.0 °C(Predicted) |
pKa | 4.76±0.10(Predicted) |
Storage Condition | -20℃ |
Use | Uses hyocholic acid is mainly used in biochemical research. |
3-ALPHA,6-ALPHA,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - Upstream Downstream Industry
3-ALPHA,6-ALPHA,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - Reference
Reference Show more | 1. [IF=6.558] Yan Cao et al."Widely quasi-quantitative analysis enables temporal bile acids-targeted metabolomics in rat after oral administration of ursodeoxycholic acid."ANALYTICA CHIMICA ACTA. 2022 Jun;1212:339885 |
3-ALPHA,6-ALPHA,7-ALPHA-TRIHYDROXY-5-BETA-CHOLAN-24-OIC ACID - Introduction
HYOCHOLIC ACID(Hyocholic acid) is an animal cholic ACID, also known as porcine bile acid. It is an organic acid present in the bile of pigs. The following is a description of the nature, use, preparation and safety information of HYOCHOLIC ACID:
Nature:
- HYOCHOLIC ACID is a white to light yellow crystalline solid with a bitter taste.
-Its chemical formula is C24H40O5, and its relative molecular mass is 408.57g/mol.
- HYOCHOLIC ACID is less soluble in water and soluble in ethanol and ether.
-It can form complexes with some metal ions.
- HYOCHOLIC ACID is an important bile ACID that helps digest food in the gallbladder.
Use:
- HYOCHOLIC ACID is commonly used for research and analysis in the laboratory.
-It can also be used as a raw material in medicines for the formulation of cholesterol-lowering drugs and bile acid replacement therapy drugs.
Method:
- HYOCHOLIC ACID can be obtained by extraction from pig bile OR by synthesis.
-The method of extracting HYOCHOLIC ACID is to extract pig bile with an organic solvent (such as diethyl ether), and then obtain HYOCHOLIC ACID with higher purity through crystallization and purification.
-The method of synthesizing HYOCHOLIC ACID usually involves a series of organic synthesis reaction steps, in which chemical reagents and catalysts are used.
Safety Information:
- HYOCHOLIC ACID is generally considered to be of low toxicity, but it still needs to be used in accordance with safe operation methods.
-When handling or contacting HYOCHOLIC ACID, follow appropriate laboratory safety procedures.
-When handling HYOCHOLIC ACID, avoid direct contact with skin and eyes, and avoid inhaling its powder or solution.
-During storage and handling, keep HYOCHOLIC ACID in a dry, airtight container to avoid contact with oxygen and moisture.
Last Update:2024-04-09 15:18:02