3-Amine-4-fluorophenylboronic acid

3-Amine-4-fluorophenylboronic acid - Names and Identifiers

Name	(3-amino-4-fluorophenyl)boronic acid
Synonyms	5-Borono-2-fluoroaniline 3-Amino-4-fluorophenylboronicacid 3-Amino-4-Fluorophenylboronic Acid 3-Amine-4-fluorophenylboronic acid 3-Amino-4-fluorobenzeneboronic acid (3-amino-4-fluorophenyl)boronic acid boronic acid, B-(3-amino-4-fluorophenyl)- Boronic acid, B-(3-amino-4-fluorophenyl)- Boronicacid, (3-amino-4-fluorophenyl)- (9CI) BORONICACID, (3-AMINO-4-FLUOROPHENYL)- (9CI) 3-Amino-4-fluorophenylboronic acid, pinacol ester (3-aMino-4-fluorophenyl)boronic acid hydrochloride
CAS	873566-75-7
InChI	InChI=1/C6H7BFNO2/c8-5-2-1-4(7(10)11)3-6(5)9/h1-3,10-11H,9H2

3-Amine-4-fluorophenylboronic acid - Physico-chemical Properties

Molecular Formula	C6H7BFNO2
Molar Mass	154.93
Density	1.34
Boling Point	346.0±52.0 °C(Predicted)
Flash Point	163.04°C
Vapor Presure	0mmHg at 25°C
Appearance	Solid
Color	White to off-white
pKa	8.59±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.555

3-Amine-4-fluorophenylboronic acid - Risk and Safety

Risk Codes

22 - Harmful if swallowed

3-Amine-4-fluorophenylboronic acid - Introduction

(3-amino-4-fluorophenyl)boronic acid is an organic compound with a chemical formula of C6H6BFO2N and a molecular weight of 157.93. It is a solid crystal, white to light yellow particles at room temperature.

The compound has a variety of functions and uses. First, it is an organoboron compound that can be used in the synthesis of ligands, catalysts and organometallic compounds. Secondly, it can also be used as an intermediate in organic synthesis and is often used in the synthesis of biologically active compounds. In addition, it can also be used in pharmaceutical research and manufacturing.

(3-amino-4-fluorophenyl) The preparation method of boronic acid can be obtained by the reaction of phenylboronic acid and 3-amino-4-fluorophenyl chloride. Specifically, phenylboronic acid and a reaction substrate are reacted by heating under suitable reaction conditions, and then the product is extracted by hydrolysis or crystallization.

When using or handling (3-amino-4-fluorophenyl)boronic acid, you need to pay attention to its safety information. Due to the special properties of organoboron, the compound has certain toxicity and corrosiveness. Therefore, appropriate personal protective equipment such as lab gloves, goggles and lab clothes should be worn during operation. In addition, inhalation of its dust or contact with the skin should be avoided to avoid discomfort. During storage, it should be kept in a dry, cool place and avoid contact with oxidants and acids.

Last Update：2024-04-09 21:04:16