Name | 3-Aminopropionitrile fumarate |
Synonyms | EINECS 218-208-7 (2E)-but-2-enedioate 3-Aminopionitrile Fumarate 3-Aminopropionitrile fumarate 3-AMINOPROPIONITRILE FUMARATE 2-Cyanoethylamine hemifumarate B-aminopropionitrile monofumarate beta-Aminopropionitrile, fumarate di(2-cyanoethylammonium) fumarate Di-beta-aminopropionitrile fumarate bis(3-aminopropiononitrile) fumarate |
CAS | 2079-89-2 |
EINECS | 218-208-7 |
InChI | InChI=1/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;2*4-2-1-3-5/h1-2H,(H,5,6)(H,7,8);2*1-2,4H2/b2-1-; |
Molecular Formula | C7H10N2O4 |
Molar Mass | 186.17 |
Melting Point | 177°C (dec.)(lit.) |
Boling Point | 355.5°C at 760 mmHg |
Flash Point | 183°C |
Water Solubility | almost transparency |
Solubility | Soluble in water |
Vapor Presure | 5.19E-06mmHg at 25°C |
Appearance | Crystalline Powder |
Color | White |
BRN | 3573532 |
Storage Condition | -20°C |
MDL | MFCD00078321 |
Use | A useful biochemical for proteomics research |
In vivo study | Twenty days after the induction of tendinitis, intralesional treatment with 3-Aminopropionitrile fumarate (2:1) (BAPN-F) is performed and the contralateral limbs receive saline. A biopsy is obtained and gross and histopathological analysis is performed on the 150 th day of the experiment. The collagen fibrillar alignment pattern in the healing area is better in the 3-Aminopropionitrile fumarate (2:1) group submitted to controlled exercise than in the other group, as observed by sonographic and histopathologic examination. The present results indicate that 3-Aminopropionitrile fumarate (2:1) in combination with controlled loading improved scar remodeling and tendon wound collagen maturation. |
Hazard Symbols | T - Toxic |
Risk Codes | 61 - May cause harm to the unborn child |
Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
WGK Germany | 3 |
RTECS | UG0700000 |
TSCA | Yes |
HS Code | 29269095 |
Toxicity | LDLo orl-rat: 800 mg/kg TJADAB 5,33,72 |
biological activity | 3-Aminopropitiontrile fumarate (2:1) is a kind of Lathyrus, which can inhibit the cross-linking between collagen (collagen). |
target | Collagen. |
in vivo research | Twenty days after the induction of tendinitis, intralesional treatment with 3-Aminopropionitrile fumarate (2:1) (BAPN-F) is performed and the contralateral limbs receive saline. A biopy is obtained and gross and histopathological analysis is performed on the 150th day of the experiment. The collagen fibrillar alignment pattern in the healing area is better in the 3-Aminopropitrile fumarate (2:1) group submitted to controlled exercise than in the other group, as observed by sonographic and histopathologic examination. The present results indicate that 3-Aminopropionitrile fumarate (2:1) in combination with controlled loading improved scar remodeling and tendon wound collagen maturation. |
category | toxic substances |
toxicity classification | poisoning |
acute toxicity | oral-rat LDL0: 800 mg/kg; Abdominal cavity-mouse LD50: 5362 mg/kg |
flammability hazard characteristics | flammable; Toxic nitrogen oxides and cyanide smoke generated by heat |
storage and transportation characteristics | warehouse ventilation and low temperature drying |
extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |
EPA chemical information | information provided by: ofmpub.epa.gov (external link) |