3-Chloro-4'-fluoropropiophenone

3-Chloro-4'-fluoropropiophenone - Names and Identifiers

Name	3-Chloro-4'-fluoropropiophenone
Synonyms	AKOS BBS-00006444 3-Chloro-4'-fluoropropiophen 3-Chloro-4-fluoropropiophenone 4'-Fluoro-β-chloropropiophenone 3-Chloro-4'-fluoropropiophenone 2-Chloro-4'-fluoropropiophenone P-FLUORO-BETA-CHLOROPROPIOPHENONE 2-Chloroethyl 4-fluorophenyl ketone 1-(4-Fluorophenyl)-3-chloro-1-propanone 3-Chloro-1-(4-fluorophenyl)-1-propanone 2-chloro-1-(4-fluorophenyl)propan-1-one 3-chloro-1-(4-fluorophenyl)propan-1-one
CAS	347-93-3
EINECS	206-475-2
InChI	InChI=1/C9H8ClFO/c1-6(12)4-7-2-3-9(11)8(10)5-7/h2-3,5H,4H2,1H3
InChIKey	AAHQPLJUSLMHHR-UHFFFAOYSA-N

3-Chloro-4'-fluoropropiophenone - Physico-chemical Properties

Molecular Formula	C9H8ClFO
Molar Mass	186.61
Density	1.2298 (estimate)
Melting Point	47-49°C(lit.)
Boling Point	100-103°C 3mm
Flash Point	198°F
Appearance	powder to crystal
Color	White to Yellow to Orange
BRN	1866785
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.508
MDL	MFCD00000991

3-Chloro-4'-fluoropropiophenone - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R52/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R22 - Harmful if swallowed
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets.
UN IDs	UN 1325 4.1/PG 2
WGK Germany	3
HS Code	29147000
Hazard Note	Irritant

3-Chloro-4'-fluoropropiophenone - Introduction

3-Chloro-4 '-fluoropropiophenone, chemical formula C9H8ClFO, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-Chloro-4 '-fluoropropiophenone is a colorless to light yellow liquid.
-Melting point: approximately − 26°C.
-Boiling point: about 140-142°C.
-Density: about 1.265g/cm³.
-Solubility: Soluble in organic solvents such as alcohols, ethers and aromatic hydrocarbons, insoluble in water.

Use:
-Chemical synthesis: It is an important organic synthesis intermediate and is widely used in the synthesis of medicines and pesticides. It can be used to synthesize drugs, dyes and other organic compounds.
-Pharmaceutical research: 3-Chloro-4 '-fluoropropiophenone is used as an important raw material and intermediate in the field of pharmaceutical research for the synthesis of various drugs.

Preparation Method:
3-Chloro-4 '-fluoropropiophenone can be prepared by fluorination, chlorination and acylation. The specific preparation method can adopt different synthetic routes according to the requirements.

Safety Information:
- 3-Chloro-4 '-fluoropropiophenone is an organic compound, which is irritating to the skin and eyes. You should pay attention to avoid contact when using it.
-During use and storage, it is necessary to avoid high temperatures and open flames while maintaining a well-ventilated working environment.
-It is necessary to strictly control its use and emissions to avoid pollution to the environment.
-In case of accidental ingestion or accidental exposure, please seek medical attention and provide relevant safety data sheets.

Last Update：2024-04-09 19:05:49