3-Chloro-5-methoxybenzeneboronic acid

3-Chloro-5-methoxybenzeneboronic acid - Names and Identifiers

Name	3-Chloro-5-methoxybenzeneboronic acid
Synonyms	QBQR CG EO1 3-Chloro-5-methoxyphenylboronic acid 3-Chloro-5-methoxybenzeneboronic acid 3-CHLORO-5-METHOXYBENZENEBORONIC ACID (3-chloro-5-methoxyphenyl)boronic acid B-(3-Chloro-5-methoxyphenyl)boronic acid boronic acid, B-(3-chloro-5-methoxyphenyl)- Boronic acid, B-(3-chloro-5-methoxyphenyl)- 3,5-Difluoro-4-(hydroxymethyl)phenylboronic acid
CAS	915201-07-9
InChI	InChI=1/C7H8BClO3/c1-12-7-3-5(8(10)11)2-6(9)4-7/h2-4,10-11H,1H3

3-Chloro-5-methoxybenzeneboronic acid - Physico-chemical Properties

Molecular Formula	C7H8BClO3
Molar Mass	186.4
Density	1.32±0.1 g/cm3(Predicted)
Melting Point	185-189°C
Boling Point	359.6±52.0 °C(Predicted)
Flash Point	171.3°C
Water Solubility	Insoluble in water.
Vapor Presure	8.51E-06mmHg at 25°C
pKa	7.12±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.544

3-Chloro-5-methoxybenzeneboronic acid - Introduction

Acid is an organic compound with the chemical formula C7H8BClO3. The following is a description of some information on the properties, uses, preparation and safety of this compound:

Nature:
-Appearance: acid is a white solid.
-Melting point: The melting point is about 168-170°C.
-Solubility: Soluble in many organic solvents such as chloroform and dichloromethane, insoluble in water.

Use:
-As an important intermediate in organic synthesis, it can be used to synthesize other complex compounds, especially organic compounds containing phenyl groups.
-It is also used as a chemical reagent, such as the preparation of fullerene transition metal catalysts in organic synthesis.

Method:
-It can be prepared by the reaction of 3-chloro-5-methoxybenzene and boric acid. A specific step may be to dissolve 3-chloro-5-methoxybenzene in dichloromethane, then gradually add boric acid to the reaction system, and heat the reaction. The product was finally purified by crystallization.

Safety Information:
-extremely acid is relatively stable under normal operating conditions, but dangerous reactions may occur in the presence of high temperature, high pressure and strong oxidants.
-During operation, attention should be paid to avoid contact with skin and eyes, and maintain good ventilation conditions. In case of contact, immediately flush the affected area with plenty of water and seek medical attention.
-This compound should be stored in a dry, cool place and away from combustibles and oxidants.

Last Update：2024-04-10 22:29:15