3-Chlorophenyl-3-propanoic acid

3-Chlorophenyl-3-propanoic acid - Names and Identifiers

Name	3-(3-Chlorophenyl)propionic acid
Synonyms	TIMTEC-BB SBB005906 ASINEX-REAG BAS 10861260 3-Chlorobenzenepropanoic acid 3-Chlorophenyl-3-propanoic acid 3-(3-CHLOROPHENYL)PROPANOIC ACID 3-(3-CHLOROPHENYL)PROPIONIC ACID 3-(3-Chlorophenyl)propionic acid 3-(3-chlorophenyl)propanoic acid Benzenepropanoic acid, 3-?chloro-
CAS	21640-48-2
EINECS	626-900-9
InChI	InChI=1/C9H9ClO2/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-3,6H,4-5H2,(H,11,12)

3-Chlorophenyl-3-propanoic acid - Physico-chemical Properties

Molecular Formula	C9H9ClO2
Molar Mass	184.62
Density	1.1989 (rough estimate)
Melting Point	72-76 °C (lit.)
Boling Point	263.86°C (rough estimate)
Flash Point	139.2°C
Vapor Presure	0.000333mmHg at 25°C
pKa	4.59(at 25℃)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.5242 (estimate)
Physical and Chemical Properties	White crystals. Melting point 77-78 °

3-Chlorophenyl-3-propanoic acid - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R41 - Risk of serious damage to eyes R43 - May cause sensitization by skin contact
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection.
WGK Germany	3
HS Code	29163990
Hazard Class	IRRITANT

3-Chlorophenyl-3-propanoic acid - Introduction

3-(3-Chlorophenyl)propionic acid is an organic compound with the chemical formula C9H9ClO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 3-(3-Chlorophenyl)propionic acid is a white crystalline solid.
-Melting point: About 75-77 ° C.
-Solubility: Soluble in ethanol, ether and carbon disulfide, slightly soluble in water.

Use:
-Pharmaceutical field: 3-(3-Chlorophenyl)propionic acid can be used as raw materials for over-the-counter drugs and prescription drugs.
-Chemical synthesis: It is also an important organic synthesis intermediate that can be used to prepare other organic compounds.

Method:
There are many ways to prepare 3-(3-Chlorophenyl)propionic acid, one of which is obtained by the condensation reaction of benzoic acid and 3-chloropropionic acid. The specific steps are as follows:
1. First, benzoic acid and 3-chloropropionic acid are added to the reactor in a suitable molar ratio.
2. To control the temperature and the concentration of chemical substances to carry out the condensation reaction, it is usually necessary to use a catalyst or an active agent to promote the reaction.
3. After the reaction is completed, the target product is obtained by crystallization or other separation and purification methods.

Safety Information:
- 3-(3-Chlorophenyl)propionic acid is a chemical substance and should be operated in accordance with laboratory safety procedures.
-Wear personal protective equipment such as gloves, safety glasses and protective clothing when in use.
-Avoid inhalation, ingestion and contact with skin, eyes, etc.
-Disposal of waste in accordance with relevant laws and regulations.

Please note that the above information is for reference only. In specific applications or operations, please follow the relevant regulations and technical guidelines.

Last Update：2024-04-10 22:29:15