3-FLUORO-P-ANISIDINE
3-fluoro-P-anisidine
CAS: 366-99-4
Molecular Formula: C7H8FNO
3-FLUORO-P-ANISIDINE - Names and Identifiers
| Name | 3-fluoro-P-anisidine |
| Synonyms | 3-FLUORO-4-ANISIDINE 3-FLUORO-P-ANISIDINE 3-fluoro-P-anisidine 4-Amino-2-fluoroanisol 4-AMINO-2-FLUOROANISOLE 3-Fluoro-4-methoxyaniline 3-FLUORO-4-METHOXYANILINE 3-Fluoro-4-methoxy-phenylamine 3-Fluoro-4-Methoxyaniline 2-Fluoro-4-Aminoanisole |
| CAS | 366-99-4 |
| EINECS | 627-615-2 |
| InChI | InChI=1/C7H8FNO/c1-10-7-3-2-5(9)4-6(7)8/h2-4H,9H2,1H3 |
3-FLUORO-P-ANISIDINE - Physico-chemical Properties
| Molecular Formula | C7H8FNO |
| Molar Mass | 141.14 |
| Density | 1.1382 (estimate) |
| Melting Point | 81-83 °C (lit.) |
| Boling Point | 135 °C/18 mmHg (lit.) |
| Flash Point | >110°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.0184mmHg at 25°C |
| Appearance | Yellow solid |
| Color | Light beige to yellow-brown |
| BRN | 2717083 |
| pKa | 4.18±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.531 |
| MDL | MFCD00075040 |
3-FLUORO-P-ANISIDINE - Risk and Safety
| Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S38 - In case of insufficient ventilation, wear suitable respiratory equipment. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S28A - |
| UN IDs | UN2811 |
| WGK Germany | 3 |
| HS Code | 29214200 |
| Hazard Note | Irritant |
| Hazard Class | 6.1 |
| Packing Group | III |
3-FLUORO-P-ANISIDINE - Introduction
3-fluoro-p-anisidine (3-fluoro-p-anisidine) is an organic compound with the formula C7H8FNO. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-fluoro-p-anisidine is a white crystalline solid.
-Melting point: about 56-58°C.
-Boiling point: about 250-252°C.
-Solubility: Soluble in alcohol, ether and ketone.
Use:
- 3-fluoro-P-anisidine can be used as an intermediate in organic synthesis.
-It can be used to prepare biologically active compounds, such as drugs and pesticides.
-Due to the particularity of its chemical structure, it can also be used in the synthesis of dyes and coatings.
Preparation Method:
3-fluoro-P-anisidine can be synthesized by the following steps:
-First, p-methoxyaniline is reacted with fluorinated sulfoxide (SO2F2) to obtain 3-fluoro-4-sulfoxylaniline sulfate.
-Then, it was treated with hydrofluoric acid to obtain 3-fluoro-p-anisidine.
Safety Information:
- 3-fluoro-p-anisidine is an organic compound and should be handled with care.
-It is an irritant, please avoid skin contact and inhalation.
-During operation, wear appropriate protective gloves and safety glasses to ensure good ventilation.
-In case of skin or eye contact, rinse immediately with plenty of water and seek medical advice.
-Keep away from flammable materials and strong oxidants during storage and handling.
Nature:
-Appearance: 3-fluoro-p-anisidine is a white crystalline solid.
-Melting point: about 56-58°C.
-Boiling point: about 250-252°C.
-Solubility: Soluble in alcohol, ether and ketone.
Use:
- 3-fluoro-P-anisidine can be used as an intermediate in organic synthesis.
-It can be used to prepare biologically active compounds, such as drugs and pesticides.
-Due to the particularity of its chemical structure, it can also be used in the synthesis of dyes and coatings.
Preparation Method:
3-fluoro-P-anisidine can be synthesized by the following steps:
-First, p-methoxyaniline is reacted with fluorinated sulfoxide (SO2F2) to obtain 3-fluoro-4-sulfoxylaniline sulfate.
-Then, it was treated with hydrofluoric acid to obtain 3-fluoro-p-anisidine.
Safety Information:
- 3-fluoro-p-anisidine is an organic compound and should be handled with care.
-It is an irritant, please avoid skin contact and inhalation.
-During operation, wear appropriate protective gloves and safety glasses to ensure good ventilation.
-In case of skin or eye contact, rinse immediately with plenty of water and seek medical advice.
-Keep away from flammable materials and strong oxidants during storage and handling.
Last Update：2024-04-09 21:04:16
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