3-Fluorobenzylmagnesium chloride 0.25M solution in diethyl ether
3-Fluorobenzylmagnesium chloride
CAS: 64168-34-9
Molecular Formula: C7H6ClFMg
3-Fluorobenzylmagnesium chloride 0.25M solution in diethyl ether - Names and Identifiers
3-Fluorobenzylmagnesium chloride 0.25M solution in diethyl ether - Physico-chemical Properties
| Molecular Formula | C7H6ClFMg |
| Molar Mass | 168.88 |
| Sensitive | Air & Moisture Sensitive |
3-Fluorobenzylmagnesium chloride 0.25M solution in diethyl ether - Risk and Safety
| Hazard Symbols | F - Flammable |
| TSCA | Yes |
| Hazard Note | Flammable |
| Hazard Class | 3 |
3-Fluorobenzylmagnesium chloride 0.25M solution in diethyl ether - Introduction
3-Fluorobenzylmagnesium chloride is an organic magnesium reagent with the chemical formula C7H6ClF2Mg. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-Fluorobenzylmagnesium chloride as a white or off-white crystalline solid.
-Solubility: It is easy to dissolve in organic solvents such as anhydrous ether and dimethylformamide.
-Stability: It is relatively stable under dry conditions, but will hydrolyze rapidly in humidity or air.
Use:
- 3-Fluorobenzylmagnesium chloride is an important Grignard reagent in organic synthesis and can be used as a nucleophile in the reaction.
-It can be used to synthesize ketones, aldehydes, ethers, acids and other functional compounds.
-It is also widely used in the fields of drug synthesis and material science.
Preparation Method:
-Under normal circumstances, 3-Fluorobenzylmagnesium chloride can be prepared by reacting 3-fluorobenzyl halohydrocarbon with magnesium in anhydrous ether or dimethylformamide.
Safety Information:
- 3-Fluorobenzylmagnesium chloride is an organic magnesium compound, so it has a certain degree of danger and needs to be operated in appropriate conditions and laboratories.
-It may cause irritation to the skin and eyes, so you need to wear appropriate personal protective equipment.
-In the handling should be carried out under good ventilation, avoid inhalation or ingestion.
-When in contact with water, it will hydrolyze rapidly and produce hydrogen gas, which needs to be handled carefully.
-During use or storage, it needs to be separated from oxidants, acids and moisture to avoid reaction with these substances.
Please note that when using or handling any chemical reagents, please carefully read and follow the safety data sheet and relevant experimental procedures.
Nature:
-Appearance: 3-Fluorobenzylmagnesium chloride as a white or off-white crystalline solid.
-Solubility: It is easy to dissolve in organic solvents such as anhydrous ether and dimethylformamide.
-Stability: It is relatively stable under dry conditions, but will hydrolyze rapidly in humidity or air.
Use:
- 3-Fluorobenzylmagnesium chloride is an important Grignard reagent in organic synthesis and can be used as a nucleophile in the reaction.
-It can be used to synthesize ketones, aldehydes, ethers, acids and other functional compounds.
-It is also widely used in the fields of drug synthesis and material science.
Preparation Method:
-Under normal circumstances, 3-Fluorobenzylmagnesium chloride can be prepared by reacting 3-fluorobenzyl halohydrocarbon with magnesium in anhydrous ether or dimethylformamide.
Safety Information:
- 3-Fluorobenzylmagnesium chloride is an organic magnesium compound, so it has a certain degree of danger and needs to be operated in appropriate conditions and laboratories.
-It may cause irritation to the skin and eyes, so you need to wear appropriate personal protective equipment.
-In the handling should be carried out under good ventilation, avoid inhalation or ingestion.
-When in contact with water, it will hydrolyze rapidly and produce hydrogen gas, which needs to be handled carefully.
-During use or storage, it needs to be separated from oxidants, acids and moisture to avoid reaction with these substances.
Please note that when using or handling any chemical reagents, please carefully read and follow the safety data sheet and relevant experimental procedures.
Last Update：2024-04-09 20:49:11
