3-Fluoropyridine-5-carboxaldehyde - Names and Identifiers
3-Fluoropyridine-5-carboxaldehyde - Physico-chemical Properties
Molecular Formula | C6H4FNO
|
Molar Mass | 125.1 |
Density | 1.269 |
Boling Point | 189℃ |
Flash Point | 68℃ |
Vapor Presure | 0.0362mmHg at 25°C |
pKa | 1.01±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.558 |
3-Fluoropyridine-5-carboxaldehyde - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36 - Irritating to the eyes
|
Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
|
Hazard Class | IRRITANT |
3-Fluoropyridine-5-carboxaldehyde - Introduction
It is an organic compound with the chemical formula C6H4FNCHO. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
1. Appearance: It is a colorless liquid with a special aroma.
2. Solubility: Its solubility in water is low, but it is soluble in many organic solvents, such as ethanol, ether and dichloromethane.
3. chemical reaction: it can be through a series of organic reaction of nucleophilic addition, alkynol reaction.
Use:
1. as an intermediate: it is often used as an intermediate in organic synthesis and can be used to synthesize compounds with pharmaceutical activity.
Chemical research: Because of its special structure and properties, it has also been widely used in some chemical research fields.
Preparation Method:
There are many preparation methods, including the following common methods:
1. Reaction: Acylation is obtained by reacting 3-oxopyridine with sodium iminofluoride or iminocopper fluoride.
2. Hydrofluoric acid catalyzed oxygen deprotection reaction: by reacting 5-azo-pyridine-3-ol with hydrofluoric acid, it is obtained.
Safety Information:
1. is an organic compound and should strictly follow laboratory safety procedures.
2. it may be irritating to the eyes, skin and respiratory tract, please avoid contact.
3. in the use of the process, should maintain good ventilation conditions, and wear appropriate protective equipment, such as gloves, safety glasses and protective masks.
4. When storing, it should be kept in a closed container, away from fire and oxidant.
5. When using and handling, pay attention to thoroughly cleaning and handling organic solvents.
6. in the disposal of waste, should comply with the relevant laws and regulations, the correct disposal of waste, to avoid pollution to the environment.
Last Update:2024-04-09 21:04:16