3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE - Names and Identifiers
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE - Physico-chemical Properties
Molecular Formula | C12H6O4
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Molar Mass | 214.17 |
Density | 1.585±0.06 g/cm3(Predicted) |
Melting Point | 281 °C |
Boling Point | 509.4±33.0 °C(Predicted) |
pKa | 7.93±0.20(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
MDL | MFCD00059759 |
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE - Risk and Safety
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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Hazard Class | IRRITANT |
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE - Upstream Downstream Industry
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE - Introduction
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE is a compound with the chemical formula C12H6O5, also known as 3-HNP ANHYDRIDE. The following is an introduction to its nature, use, preparation and safety information:
Nature:
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE is a white to light yellow solid that is soluble in organic solvents such as methylene chloride, ethanol and ether, but insoluble in water. It has poor deliquescence and thermal stability.
Use:
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE has many applications in organic synthesis. It can be used as an intermediate in organic synthesis for the preparation of other organic compounds. It can also be used as a raw material for dyes and fluorescent probes for biological and medicinal chemistry research.
Method:
The preparation of 3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE is usually achieved by the hydrolysis reaction of methyl 1,8-naphthalene dicarboxylic acid. First, methyl 1,8-naphthalenedicarboxylic acid is reacted with water or an aqueous alcohol solution to form 3-hydroxy-1, 8-naphthalenedicarboxylic acid. It is then dehydrated by heating 3-HYDROXY-1, 8-naphthalenedicarboxylic acid to form 3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE.
Safety Information:
3-HYDROXY-1,8-NAPHTHALIC ANHYDRIDE has low toxicity, but it is still necessary to pay attention to safe operation. It may be irritating to the eyes, skin and respiratory tract. Wear appropriate protective goggles, gloves and protective mask during operation. Avoid inhaling dust or contact with skin. If you come into contact with a large amount of the compound, wash the affected area and seek medical help. When storing, it should be kept in a closed container, away from open flame and high temperature.
Last Update:2024-04-09 21:01:54