3-HYDROXYPYRIDINE-2-CARBOXAMIDE

3-HYDROXYPYRIDINE-2-CARBOXAMIDE - Names and Identifiers

Name	3-Hydroxypicolinamide
Synonyms	Hydroxypicolinamide 3-Hydroxypicolinamide 3-HYDROXYPICOLINAMIDE 3-Hydroxypicolineamide 3-HYDROXY-2-PYRIDINECARBOXAMIDE 3-HYDROXYPYRIDINE-2-CARBOXAMIDE 3-Hydroxypyridine-2-carboxamide 2-Pyridinecarboxamide,3-hydroxy-(9CI) 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID AMIDE
CAS	933-90-4
EINECS	213-274-3
InChI	InChI=1/C6H6N2O2/c7-6(10)5-4(9)2-1-3-8-5/h1-3,9H,(H2,7,10)

3-HYDROXYPYRIDINE-2-CARBOXAMIDE - Physico-chemical Properties

Molecular Formula	C6H6N2O2
Molar Mass	138.12
Density	1.384±0.06 g/cm3(Predicted)
Melting Point	193-197 °C (lit.)
Boling Point	479.3±30.0 °C(Predicted)
Flash Point	243.7°C
Vapor Presure	8.24E-10mmHg at 25°C
Appearance	powder to crystal
Color	White to Almost white
pKa	15.26±0.50(Predicted)
Storage Condition	Room Temprature
Refractive Index	1.622
MDL	MFCD00006302

3-HYDROXYPYRIDINE-2-CARBOXAMIDE - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3

3-HYDROXYPYRIDINE-2-CARBOXAMIDE - Introduction

3-Hydroxypicolinamide(3-Hydroxypicolinamide) is an organic compound with the chemical formula C6H6N2O2.

The following is about the properties of 3-Hydroxypicolinamide:
1. Appearance: 3-Hydroxypicolinamide is a white to off-white solid crystal.
2. Solubility: It can be dissolved in water and soluble in organic solvents such as ethanol and chloroform.
3. Melting Point: The melting point of 3-Hydroxypicolinamide is about 176-179°C.

The main application areas of 3-Hydroxypicolinamide include chemical synthesis and the pharmaceutical industry. It is used as an intermediate in organic synthesis and can be used to synthesize a variety of organic compounds, such as drugs, dyes, coordination compounds, etc. Other specific applications include metal ion chelators, enzyme catalysts, and fluorescent probes.

The preparation method of 3-Hydroxypicolinamide can be achieved by the condensation reaction of pyridine-2-amide and aldehyde. This reaction requires a suitable condensing agent and solvent and is carried out at an appropriate temperature and time.

Regarding the safety information of 3-Hydroxypicolinamide, due to the lack of relevant literature reports, its toxicity and safety are not clear. When in use, should strictly follow the chemical laboratory safety procedures, wear appropriate protective equipment (such as gloves, goggles and protective clothing) for operation. Any experiment or application of a chemical substance should be preceded by an assessment and determination of its safety.

Last Update：2024-04-09 19:05:53