3-Phenyl-1,4,2-dioxazol-5-one - Names and Identifiers
3-Phenyl-1,4,2-dioxazol-5-one - Physico-chemical Properties
Molecular Formula | C8H5NO3
|
Molar Mass | 163.13 |
Density | 1.36±0.1 g/cm3(Predicted) |
Melting Point | 63 °C |
Boling Point | 214.9±23.0 °C(Predicted) |
3-Phenyl-1,4,2-dioxazol-5-one - Upstream Downstream Industry
3-Phenyl-1,4,2-dioxazol-5-one - Introduction
3-Phenyl-1,4,2-dioxazolidin-5-one is an organic compound with the chemical formula C11H9NO3. The following is a detailed description of the nature, use, preparation and safety information of 3-Phenyl-1,4,2-dioxazolidin-5-one:
Nature:
-Appearance: 3-Phenyl-1,4,2-dioxazolidin-5-one is a white crystalline solid.
-Solubility: It has good solubility in common organic solvents such as ethanol, dimethylformamide and dichloromethane.
-Melting point: Its melting point is generally between 100-103 ° C.
Use:
- 3-Phenyl-1,4,2-dioxazolidin-5-one is an effective synthetic intermediate and is widely used in the preparation of other compounds in organic synthesis.
-It has certain applications in the field of medicinal chemistry and can be used to synthesize compounds with antibacterial, anti-biofilm and antiviral activities.
Method:
- 3-Phenyl-1,4,2-dioxazolidin-5-one can be obtained by the reaction of benzyl alcohol and Formic Anhydride under alkaline conditions.
-The specific preparation method is as follows: first, benzyl alcohol and sodium bicarbonate are mixed, stirred in an organic solvent such as methanol, Formic Anhydride is added, and heated under alkaline conditions. After the reaction was carried out, the product 3-Phenyl-1,4,2-dioxazolidin-5-one was purified by crystallization.
Safety Information:
- 3-Phenyl-1,4,2-dioxazolidin-5-one is generally stable under normal use and storage conditions. However, it is an organic compound, so it is still necessary to comply with general chemical safety practices.
-Personal protective equipment such as protective gloves, safety glasses and laboratory coats are recommended for operation. Avoid inhalation, ingestion and skin contact.
-When disposing of waste, correct disposal according to local regulations to avoid pollution to the environment.
Last Update:2024-04-09 20:49:11