3-Phenylpropylzinc bromide
3-Phenylpropylzinc bromide
CAS: 626207-42-9
Molecular Formula: C9H11BrZn
3-Phenylpropylzinc bromide - Names and Identifiers
| Name | 3-Phenylpropylzinc bromide |
| Synonyms | 3-Phenylpropylzinc bromide 3-PHENYL-1-PROPYLZINC BROMIDE 3-Phenylpropylzinc bromide, Packaged under Argon in resealable ChemSeal? bottles |
| CAS | 626207-42-9 |
3-Phenylpropylzinc bromide - Physico-chemical Properties
| Molecular Formula | C9H11BrZn |
| Molar Mass | 264.48 |
| Exposure Limit | ACGIH: TWA 50 ppm; STEL 100 ppm (Skin)OSHA: TWA 200 ppm(590 mg/m3)NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3) |
| Sensitive | Air Sensitive |
3-Phenylpropylzinc bromide - Risk and Safety
| Hazard Class | 4.3 |
3-Phenylpropylzinc bromide - Introduction
3-Phenylpropylzinc bromide is an organic zinc reagent with a chemical formula of C9H9BrZn. Its main properties are as follows:
1. Appearance: 3-Phenylpropylzinc bromide is a colorless to light yellow liquid.
2. solubility: it is soluble in ether, toluene and other organic solvents.
3. activity: 3-Phenylpropylzinc bromide is a kind of organometallic compounds with nucleophilic properties, which can react with some unstable chemical substances.
4. Stability: It is relatively stable under dry conditions, but it will react with moisture and decompose.
The main uses of 3-Phenylpropylzinc bromide include:
1. organic synthesis: it can be used as a strong nucleophile in organic synthesis, commonly used in active halogenated hydrocarbons, ketones and aldehydes nucleophilic substitution reaction, such as Grignard reaction.
2. Catalyst: As a derivative of organic zinc reagent, it can be used to catalyze the reaction between oxamide and selective reducing agent.
The method for preparing 3-Phenylpropylzinc bromide is usually:
1. In a dry organic solvent, zinc bromide is reacted with 3-phenylpropyl halide, usually at low temperature.
2. The reactant is separated from the reaction mixture, usually by a method such as extraction or distillation.
Precautions and Safety Information:
1. As 3-Phenylpropylzinc bromide is an organic zinc reagent with nucleophilic properties, it is necessary to avoid contact with moisture and water during operation to prevent rapid decomposition.
2. 3-Phenylpropylzinc bromide have certain toxicity and irritation, and it is necessary to strictly abide by the safety operation regulations and wear appropriate personal protective equipment.
3. during operation and storage, 3-Phenylpropylzinc bromide should be separated from other organic reagents, oxidants and fire sources to avoid accidents.
4. Waste treatment: The treated 3-Phenylpropylzinc bromide should be safely treated according to local regulations, and should not be discharged or poured into the sewer at will.
1. Appearance: 3-Phenylpropylzinc bromide is a colorless to light yellow liquid.
2. solubility: it is soluble in ether, toluene and other organic solvents.
3. activity: 3-Phenylpropylzinc bromide is a kind of organometallic compounds with nucleophilic properties, which can react with some unstable chemical substances.
4. Stability: It is relatively stable under dry conditions, but it will react with moisture and decompose.
The main uses of 3-Phenylpropylzinc bromide include:
1. organic synthesis: it can be used as a strong nucleophile in organic synthesis, commonly used in active halogenated hydrocarbons, ketones and aldehydes nucleophilic substitution reaction, such as Grignard reaction.
2. Catalyst: As a derivative of organic zinc reagent, it can be used to catalyze the reaction between oxamide and selective reducing agent.
The method for preparing 3-Phenylpropylzinc bromide is usually:
1. In a dry organic solvent, zinc bromide is reacted with 3-phenylpropyl halide, usually at low temperature.
2. The reactant is separated from the reaction mixture, usually by a method such as extraction or distillation.
Precautions and Safety Information:
1. As 3-Phenylpropylzinc bromide is an organic zinc reagent with nucleophilic properties, it is necessary to avoid contact with moisture and water during operation to prevent rapid decomposition.
2. 3-Phenylpropylzinc bromide have certain toxicity and irritation, and it is necessary to strictly abide by the safety operation regulations and wear appropriate personal protective equipment.
3. during operation and storage, 3-Phenylpropylzinc bromide should be separated from other organic reagents, oxidants and fire sources to avoid accidents.
4. Waste treatment: The treated 3-Phenylpropylzinc bromide should be safely treated according to local regulations, and should not be discharged or poured into the sewer at will.
Last Update：2024-04-10 22:29:15
