3-Piperidinol, 1-(phenylmethyl)-, (3S)-

3-Piperidinol, 1-(phenylmethyl)-, (3S)- - Names and Identifiers

Name	(3S)-1-benzylpiperidin-3-ol
Synonyms	(S)-1-BENZYL-PIPERIDINOL (S)-1-Benzyl-3-piperidinol (3S)-1-Benzyl-3-piperidinol (S)-1-BENZYL-PIPERIDIN-3-OL (3S)-1-benzylpiperidin-3-ol (S)-1-Benzyl-3-hydroxypiperidi (S)-1-BENZYL-3-HYDROXYPIPERIDINE (S)-N-BENZYL-3-HYDROXYPIPERIDINE (S)-1-Benzyl-3-Hydroxypiperidine (S)-1-N-BENZYL-3-HYDROXY-PIPERIDINE (S)-(+)-1-Benzyl-3-hydroxypiperidine 3-PIPERIDINOL, 1-(PHENYLMETHYL)-, (3S)- 3-Piperidinol, 1-(phenylmethyl)-, (3S)-
CAS	91599-79-0
InChI	InChI=1/C12H17NO/c14-12-7-4-8-13(10-12)9-11-5-2-1-3-6-11/h1-3,5-6,12,14H,4,7-10H2/t12-/m0/s1

3-Piperidinol, 1-(phenylmethyl)-, (3S)- - Physico-chemical Properties

Molecular Formula	C12H17NO
Molar Mass	191.27
Density	1.106±0.06 g/cm3(Predicted)
Boling Point	296.8±33.0 °C(Predicted)
Flash Point	113°C
Vapor Presure	0.000631mmHg at 25°C
pKa	14.82±0.20(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	n20/D 1.545±0.002

3-Piperidinol, 1-(phenylmethyl)-, (3S)- - Risk and Safety

Hazard Symbols	T - Toxic
Risk Codes	R25 - Toxic if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN2810 6.1/PG 3

3-Piperidinol, 1-(phenylmethyl)-, (3S)- - Introduction

(3S)-1-benzylpiperidin-3-ol is a chiral compound with the chemical name (3S)-1-benzylpiperidin-3-ol. It is a white crystalline solid, soluble in water and organic solvents.

This compound has a wide range of applications in the pharmaceutical field. As a chiral intermediate, it can be used in the synthesis of other drug molecules, such as antipsychotics, sedatives and tremor-like drugs.

The preparation of (3S)-1-benzylpiperidin-3-ol can be achieved by reducing the corresponding chiral precursor piperidine. Specific steps include esterifying or acylating piperidine and then reducing it to the target product under the action of a reducing agent.

Regarding safety information, this compound is relatively safe under normal circumstances. However, as any chemical, it should be used with proper handling and protective measures to avoid contact with skin and eyes. In the use of the process to maintain good ventilation, and comply with the relevant safety procedures. If necessary, the operation should be carried out in a specialized laboratory or industrial environment.

Last Update：2024-04-09 20:45:29