3-Pyridinecarbonitrile, 2-fluoro-6-(1-pyrrolidinyl)-
2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile
CAS: 1228665-87-9
Molecular Formula: C10H10FN3
3-Pyridinecarbonitrile, 2-fluoro-6-(1-pyrrolidinyl)- - Names and Identifiers
| Name | 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile |
| Synonyms | 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile 3-Pyridinecarbonitrile, 2-fluoro-6-(1-pyrrolidinyl)- |
| CAS | 1228665-87-9 |
3-Pyridinecarbonitrile, 2-fluoro-6-(1-pyrrolidinyl)- - Physico-chemical Properties
| Molecular Formula | C10H10FN3 |
| Molar Mass | 191.2 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD15530300 |
3-Pyridinecarbonitrile, 2-fluoro-6-(1-pyrrolidinyl)- - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
3-Pyridinecarbonitrile, 2-fluoro-6-(1-pyrrolidinyl)- - Introduction
2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile (2-fluoro-6-(pyrrolin-1-yl) nicotinic acid nitrile) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Usually a white crystalline solid.
-Molecular formula: C12H11FN2
-Molecular weight: 202.23g/mol
-Melting point: about 118-120°C
-Solubility: Soluble in some organic solvents (such as dichloromethane, dimethylformamide).
Use:
- 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile are useful as pharmaceutical intermediates.
-It can be used to synthesize biologically active compounds.
Preparation Method:
2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile can be synthesized by a variety of methods. A common method is to introduce a fluorine atom by n-substitution of p-fluorophenyl ethanone and a pyrroline group by reaction with pyrroline.
Safety Information:
2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile, as an organic compound, should be treated with caution. Appropriate laboratory safety and protective measures are required.
-It may be irritating to the skin, eyes, and respiratory system, so direct contact should be avoided during operation. In case of contact with eyes or skin, rinse immediately with plenty of water and seek medical help.
-During operation, maintain a good ventilation system and avoid inhaling its vapor or dust.
-When storing and handling, comply with local regulations and keep it away from high temperatures, open flames and oxidizing agents.
Nature:
-Appearance: Usually a white crystalline solid.
-Molecular formula: C12H11FN2
-Molecular weight: 202.23g/mol
-Melting point: about 118-120°C
-Solubility: Soluble in some organic solvents (such as dichloromethane, dimethylformamide).
Use:
- 2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile are useful as pharmaceutical intermediates.
-It can be used to synthesize biologically active compounds.
Preparation Method:
2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile can be synthesized by a variety of methods. A common method is to introduce a fluorine atom by n-substitution of p-fluorophenyl ethanone and a pyrroline group by reaction with pyrroline.
Safety Information:
2-Fluoro-6-(pyrrolidin-1-yl)nicotinonitrile, as an organic compound, should be treated with caution. Appropriate laboratory safety and protective measures are required.
-It may be irritating to the skin, eyes, and respiratory system, so direct contact should be avoided during operation. In case of contact with eyes or skin, rinse immediately with plenty of water and seek medical help.
-During operation, maintain a good ventilation system and avoid inhaling its vapor or dust.
-When storing and handling, comply with local regulations and keep it away from high temperatures, open flames and oxidizing agents.
Last Update：2024-04-09 15:18:09
