3-Pyrrolidinecarboxylic acid, 4-(2-fluorophenyl)-1-(phenylmethyl)-, ethyl ester
Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate
CAS: 874990-49-5
Molecular Formula: C20H22FNO2
3-Pyrrolidinecarboxylic acid, 4-(2-fluorophenyl)-1-(phenylmethyl)-, ethyl ester - Names and Identifiers
3-Pyrrolidinecarboxylic acid, 4-(2-fluorophenyl)-1-(phenylmethyl)-, ethyl ester - Physico-chemical Properties
| Molecular Formula | C20H22FNO2 |
| Molar Mass | 327.39 |
| Density | 1.166±0.06 g/cm3(Predicted) |
| Boling Point | 403.6±45.0 °C(Predicted) |
| pKa | 7.61±0.60(Predicted) |
3-Pyrrolidinecarboxylic acid, 4-(2-fluorophenyl)-1-(phenylmethyl)-, ethyl ester - Introduction
Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate is an organic compound, commonly known by the abbreviation Et-Bz-Fp-Pyr-CO2Et.
Nature:
-Appearance: White solid
-Molecular formula: C23H22FNO2
-Molecular weight: 365.43g/mol
-Melting Point: 82-84 ℃
-Boiling point: 419.7 ℃
-Stable exposure to air, but hydrolysis may occur under strong acid conditions.
Use:
- Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate is a pyruvate receptor agonist, which can be used as a research compound to explore new biological activities, for example as a precursor compound of an anticancer drug or analgesic.
Method:
The synthesis of-Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate usually involves a series of organic synthesis steps. A common preparation method is to generate 1-benzyl pyrrolidine by reacting benzyl amine with an appropriate halogenated hydrocarbon, and then introduce 2-fluorophenyl by reacting aryl lithium reagent with aryl halogenated hydrocarbon, finally, the carboxylic acid group is introduced by acid catalysis or acid chloride reaction to obtain the target product.
Safety Information:
There are limited safety and toxicity data for the-Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate. Appropriate personal protective measures should be taken during handling, such as wearing gloves, goggles and protective clothing.
-The compound should be handled under well-ventilated laboratory conditions, avoiding skin contact and inhalation.
-Laboratory work involving this compound should follow the relevant safety procedures and laboratory rules and regulations.
-When handling and disposing of this compound, local laws and regulations should be observed to avoid pollution to the environment.
Nature:
-Appearance: White solid
-Molecular formula: C23H22FNO2
-Molecular weight: 365.43g/mol
-Melting Point: 82-84 ℃
-Boiling point: 419.7 ℃
-Stable exposure to air, but hydrolysis may occur under strong acid conditions.
Use:
- Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate is a pyruvate receptor agonist, which can be used as a research compound to explore new biological activities, for example as a precursor compound of an anticancer drug or analgesic.
Method:
The synthesis of-Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate usually involves a series of organic synthesis steps. A common preparation method is to generate 1-benzyl pyrrolidine by reacting benzyl amine with an appropriate halogenated hydrocarbon, and then introduce 2-fluorophenyl by reacting aryl lithium reagent with aryl halogenated hydrocarbon, finally, the carboxylic acid group is introduced by acid catalysis or acid chloride reaction to obtain the target product.
Safety Information:
There are limited safety and toxicity data for the-Trans ethyl -1-benzyl-4-(2-fluorophenyl)pyrrolidine-3-carboxylate. Appropriate personal protective measures should be taken during handling, such as wearing gloves, goggles and protective clothing.
-The compound should be handled under well-ventilated laboratory conditions, avoiding skin contact and inhalation.
-Laboratory work involving this compound should follow the relevant safety procedures and laboratory rules and regulations.
-When handling and disposing of this compound, local laws and regulations should be observed to avoid pollution to the environment.
Last Update：2024-04-09 02:00:52
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