3-Trifluoromethyl-4-Fluoro Phenol

3-Trifluoromethyl-4-Fluoro Phenol - Names and Identifiers

Name	4-Fluoro-3-(trifluoromethyl)phenol
Synonyms	4-Fluoro-3-trifluoromethyl à,à,à-4-tetrafluoro-m-cresol 4-fluoro-3-trifluoromethylphenol 3-Trifluoromethyl-4-fluorophenol 4-fluoro-3-trifluoromethyl phenol 3-Trifluoromethyl-4-Fluoro Phenol 4-Fluoro-3-(trifluoromethyl)phenol 4-FLUORO-3-(TRIFLUOROMETHYL)PHENOL 2-Fluoro-5-Hydroxybenzotrifluoride 2-FLUORO-5-HYDROXYBENZOTRIFLUORIDE alpha,alpha,alpha-4-Tetrafluoro-m-cresol 3-Trifluoromethyl-4-Fluoro Phenol 3-Trifluoromethyl-4-Fluorophenol
CAS	61721-07-1
EINECS	432-560-0
InChI	InChI=1/C7H4F4O/c8-6-2-1-4(12)3-5(6)7(9,10)11/h1-3,12H

3-Trifluoromethyl-4-Fluoro Phenol - Physico-chemical Properties

Molecular Formula	C7H4F4O
Molar Mass	180.1
Density	1.145
Melting Point	17 °C
Boling Point	84-86°C 15mm
Flash Point	90°C
Vapor Presure	0.164mmHg at 25°C
Appearance	powder to lump to clear liquid
Color	White or Colorless to Orange to Green
BRN	2098736
pKa	8.97±0.18(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.45
MDL	MFCD00043875
Physical and Chemical Properties	Light yellow liquid

3-Trifluoromethyl-4-Fluoro Phenol - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28 - After contact with skin, wash immediately with plenty of soap-suds. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	2922
HS Code	29081990
Hazard Note	Toxic
Hazard Class	8
Packing Group	II

3-Trifluoromethyl-4-Fluoro Phenol - Introduction

4-Fluoro-3-(trifluoromethyl)phenol is an organic compound with the chemical formula C7H4F4O. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: 4-Fluoro-3-(trifluoromethyl)phenol is a white crystalline solid.
-Solubility: The compound is soluble in some organic solvents, such as ethanol and dichloromethane, but insoluble in water.
-Melting point: The melting point of this compound is about 99-101°C.
-Stability: 4-Fluoro-3-(trifluoromethyl)phenol is relatively stable at room temperature, but may decompose under high temperature or light.

Use:
-Chemical intermediate: 4-Fluoro-3-(trifluoromethyl)phenol can be used as an intermediate in organic synthesis, which is widely used in drug synthesis, pesticide synthesis and dye synthesis.

Preparation Method:
- 4-Fluoro-3-(trifluoromethyl)phenol is usually prepared by fluorination and trifluoromethylation of phenol. The specific preparation method can be obtained by first reacting phenol with a fluorinating agent to obtain 4-fluorophenol, and then reacting 4-fluorophenol with a trifluoromethylating agent to finally obtain the target product.

Safety Information:
-The compound is relatively stable under general use conditions, but you still need to pay attention to avoid high temperature and light.
-Due to the particularity of its chemical properties, it is recommended to wear appropriate protective measures during operation, such as eye and skin protection.
-The compound should be used and stored in accordance with relevant chemical safety procedures and guidelines, and to ensure that proper storage and handling methods are followed.

Please note that this information is for informational purposes only. Please follow the laboratory's safety instructions and local laws and regulations when using or handling this compound.

Last Update：2024-04-09 19:05:51