3-amino-4-(methylamino)benzonitrile

3-amino-4-(methylamino)benzonitrile - Names and Identifiers

Name	3-amino-4-(methylamino)benzonitrile
Synonyms	3-amino-4-(methylamino)benzonitrile 3-AMINO-4-(METHYLAMINO)BENZONITRILE Benzonitrile, 3-amino-4-(methylamino)- Benzonitrile, 3-amino-4-(methylamino)- (9CI)
CAS	64910-46-9
InChI	InChI=1/C8H9N3/c1-11-8-3-2-6(5-9)4-7(8)10/h2-4,11H,10H2,1H3

3-amino-4-(methylamino)benzonitrile - Physico-chemical Properties

Molecular Formula	C8H9N3
Molar Mass	147.18
Density	1.15±0.1 g/cm3(Predicted)
Melting Point	139 °C
Boling Point	346.8±32.0 °C(Predicted)
Flash Point	163.529°C
Vapor Presure	0mmHg at 25°C
pKa	4.74±0.11(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.593

3-amino-4-(methylamino)benzonitrile - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3439

3-amino-4-(methylamino)benzonitrile - Introduction

3-amino-4-(methylamino)benzonitrile is an organic compound with the chemical formula C8H9N3. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: 3-amino-4-(methylamino)benzonitrile is a white to light yellow solid.
-Solubility: It is soluble in some organic solvents, such as ethanol and dimethyl sulfoxide.
-Melting point: Its melting point range is 156-159°C.

Use:
-Drugs: 3-amino-4-(methylamino)benzonitrile can be used to prepare some drugs, such as anti-cancer drugs and anti-tuberculosis drugs.
-Industry: It can also be used for the synthesis of other compounds in organic synthesis.

Preparation Method:
The preparation of 3-amino-4-(methylamino)benzonitrile can generally be carried out by the following steps:
-First, under certain conditions, 3-aminobenzaldehyde and methylamine are reacted to produce 3-amino-4-methylaminobenzaldehyde.
-Then, 3-amino-4-methylaminobenzaldehyde is reacted with sodium cyanide to generate 3-amino-4-(methylamino)benzonitrile.

Safety Information:
The 3-amino-4-(methylamino)benzonitrile has limited toxicity information and therefore needs to be handled with caution. Wear appropriate protective equipment, such as lab gloves and goggles, when operating. Avoid skin contact and inhalation of dust or vapors. In case of accidental use or other physical contact, seek medical attention immediately.

Last Update：2024-04-09 21:01:54