3-boronobenzyl bromide

3-boronobenzyl bromide - Names and Identifiers

Name	(3-Bromomethylphenyl)boronic acid
Synonyms	RARECHEM AH PB 0062 3-boronobenzyl bromide 3-Bromomethylphenylboronic 3-BROMOMETHYLPHENYLBORONIC ACID 3-Bromomethylphenylboronic acid M-(BROMOMETHYL)PHENYLBORONIC ACID 3-(Bromomethyl)Phenylboronic Acid (3-Bromomethylphenyl)boronic acid 3-(BROMOMETHYL)BENZENEBORONIC ACID 3-(Bromomethyl)benzeneboronic acid 3-Boronobenzyl bromide~3-(Bromomethyl)phenylboronic acid
CAS	51323-43-4
EINECS	626-228-6
InChI	InChI=1/C7H8BBrO2/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4,10-11H,5H2

3-boronobenzyl bromide - Physico-chemical Properties

Molecular Formula	C7H8BBrO2
Molar Mass	214.85
Density	1.57±0.1 g/cm3(Predicted)
Melting Point	214-216°C
Boling Point	359.1±44.0 °C(Predicted)
Flash Point	171°C
Solubility	soluble in Methanol
Vapor Presure	8.83E-06mmHg at 25°C
Appearance	Crystalline Powder
Color	White to tan
BRN	3246618
pKa	8.11±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.582
MDL	MFCD01632207

3-boronobenzyl bromide - Risk and Safety

Risk Codes	R34 - Causes burns R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing.
UN IDs	3261
WGK Germany	3
HS Code	29319090
Hazard Note	Irritant
Hazard Class	8
Packing Group	II

3-boronobenzyl bromide - Introduction

(3-Bromomethylphenyl)boronic acid is an organic compound with the chemical formula C7H8BrBO2. The following is a description of its nature, use, formulation and safety information:

Nature:
-Appearance: Colorless solid
-melting point: about 110-115 degrees Celsius
-Soluble: Soluble in common organic solvents, such as ethanol and dimethyl sulfoxide

Use:
- (3-Bromometylphenyl) boronic acid is often used as an important reagent and intermediate in organic synthesis.
-It can be used to construct the skeleton of organic molecules and participate in chemical reactions, such as nucleophilic substitution reactions, palladium-catalyzed coupling reactions and arylborylation reactions.
-In the field of drug synthesis, it is also widely used to introduce benzene rings and methyl groups.

Preparation Method:
- (3-Bromomethylphenyl)boronic acid can be prepared by the reaction of p-phenylboronic acid and methyl bromide. The reaction is generally carried out under basic conditions, and the base can improve the speed and yield of the reaction.

Safety Information:
- (3-Bromomethylphenyl)boronic acid may be irritating to the eyes, skin, and respiratory tract. Appropriate safety measures should be taken during operation, including wearing protective glasses, gloves and masks.
-Store in an airtight container, away from ignition and oxidizing agents.
-Operations involving this compound should be carried out in a well-ventilated place, avoiding inhalation and contact with skin.
-Observe relevant safety procedures and correct waste disposal methods when handling the compound.

Last Update：2024-04-09 02:00:46