Molecular Formula | C6HBrF4 |
Molar Mass | 228.97 |
Density | 1.883g/mLat 25°C(lit.) |
Boling Point | 143-143.5°C(lit.) |
Flash Point | 129°F |
Water Solubility | Not miscible or difficult to mix in water. |
Vapor Presure | 0.136mmHg at 25°C |
Appearance | clear liquid |
Specific Gravity | 1.883 |
Color | Colorless to Almost colorless |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.469(lit.) |
Physical and Chemical Properties | Colorless to light yellow liquid. The boiling point is 142 ℃, the flash point is 47 ℃, the refractive index is 1.4670, and the specific gravity is 1.862. |
Risk Codes | R10 - Flammable R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S37/39 - Wear suitable gloves and eye/face protection |
UN IDs | UN 1993 3/PG 3 |
WGK Germany | 3 |
HS Code | 29039990 |
Hazard Note | Irritant |
Hazard Class | 3 |
Packing Group | III |
Introduction | 1-bromo-2, 3,5, 6-tetrafluorobenzene is a halogenated polyfluorobenzene compound. Polyfluoro-aromatics containing one or two other haloaromatic atoms in the aromatic ring may be used to introduce the polyfluoro moiety into a variety of molecules. Compounds containing such fragments are required in medicine, agrochemistry, and the manufacture of various functional materials. The pentafluorophenyl-containing compound can be used in pharmaceutical chemistry, electron transport devices, light emitting diodes, printing industry, liquid crystal displays, fluorine-containing two-phase ligands, and the like. |
preparation | add 2,3,5, 6-tetrafluorobenzoic acid potassium salt (100g) to dimethylformamide (250ml) in a Glass reactor equipped with a mechanical stirrer, a dropping funnel, a separator, a libper condenser, an adapter, and a receiving bottle, the reaction mixture was heated to 140 °c, bromotrichloromethane (85g) was added in such a way as to maintain a temperature of 140-143 °c while distilling off the resulting product. This process continues until the end of the deflation. The distillate and Cube were mixed and washed with two volumes of 15% perchloric acid. The lower layer (organic) was separated, steam distilled, then dried and distilled with cacl2. 1-bromo-2, 3,5, 6-tetrafluorobenzene (89g) was obtained with a boiling point of 144 ° C. And a yield of 91%. |
Use | Pharmaceutical, pesticide, liquid crystal material intermediates. |