3-fluoro-4-nitrobenzene-1-sulfonyl chloride - Names and Identifiers
3-fluoro-4-nitrobenzene-1-sulfonyl chloride - Physico-chemical Properties
Molecular Formula | C6H3ClFNO4S
|
Molar Mass | 239.61 |
Density | 1.685±0.06 g/cm3(Predicted) |
Melting Point | 45-48°C |
Boling Point | 126°C/0.25mm |
Flash Point | 167.2°C |
Vapor Presure | 7.62E-05mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Moisture Sensitive |
Refractive Index | 1.568 |
3-fluoro-4-nitrobenzene-1-sulfonyl chloride - Risk and Safety
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | 3261 |
Hazard Class | 8 |
3-fluoro-4-nitrobenzene-1-sulfonyl chloride - Introduction
is an organic compound, chemical formula for C6H3ClFNO4S, belonging to the aromatic sulfonyl chloride derivatives. It is a colorless to pale yellow crystal, soluble in organic solvents such as ether and methylene chloride.
It can be used as a reagent in organic synthesis and has important applications in drug synthesis and pharmaceutical chemistry research. It is commonly used in the synthesis of sulfamoyl chlorides and sulfamoyl esters, and can be used as a pharmaceutical intermediate or a synthetic precursor of biologically active molecules.
The preparation can be carried out by reacting p-nitroaniline with sulfonyl chloride, and then undergoing a fluorination reaction.
In terms of safety, it is an irritating compound that may cause inflammation and irritation in contact with the skin or eyes. Appropriate protective measures should be taken during operation, including wearing protective gloves, glasses and protective clothing. At the same time, it should be operated in a well-ventilated environment to avoid inhaling gas and flying dust.
Last Update:2024-04-09 21:11:58