4'-Fluoro-2-phenylacetophenone
4'-Fluoro-2-phenylacetophenone
CAS: 347-84-2
Molecular Formula: C14H11FO
4'-Fluoro-2-phenylacetophenone - Names and Identifiers
| Name | 4'-Fluoro-2-phenylacetophenone |
| Synonyms | Atorvastatin Impurity 78 BENZYL 4-FLUOROPHENYL KETONE 4'-FLUORO-2-PHENYLACETOPHENONE 4'-Fluoro-2-phenylacetophenone 1-(4-FLUOROPHENYL)-2-PHENYLETHANONE 1-(4-Fluorophenyl)-2-phenylethanone 1-(4-fluorophenyl)-2-phenylethan-1-one |
| CAS | 347-84-2 |
| InChI | InChI=1/C14H11FO/c15-13-8-6-12(7-9-13)14(16)10-11-4-2-1-3-5-11/h1-9H,10H2 |
4'-Fluoro-2-phenylacetophenone - Physico-chemical Properties
| Molecular Formula | C14H11FO |
| Molar Mass | 214.23 |
| Density | 1.152±0.06 g/cm3(Predicted) |
| Melting Point | 83-84 |
| Boling Point | 332.9±17.0 °C(Predicted) |
| Flash Point | 137.9°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Vapor Presure | 0.000141mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | 2-8°C |
| Refractive Index | 1.567 |
| MDL | MFCD00017960 |
4'-Fluoro-2-phenylacetophenone - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Class | IRRITANT |
4'-Fluoro-2-phenylacetophenone - Introduction
4 '-Fluoro-2-phenylacetophenone(4'-Fluoro-2-phenylacetophenone) is a chemical compound with the formula C14H11FO. It is a solid, usually in the form of white to pale yellow crystals or powder. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White to light yellow crystal or powder
-Molecular weight: 224.24g/mol
-Melting Point: 84-88°C
-Boiling point: 353°C
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane, slightly soluble in water.
Use:
-Chemical synthesis: 4 '-Fluoro-2-phenylacetophenone can be used as intermediates in organic synthesis, such as for the synthesis of drugs, pesticides and dyes.
-Research use: It is also commonly used in catalytic reactions and organic synthesis reactions in research.
Preparation Method:
The synthesis of 4 '-Fluoro-2-phenylacetophenone can be carried out by a variety of methods. A common method is to introduce fluorine atoms by reacting 2-phenylacetophenone with a fluorinating agent, such as hydrogen fluoride or boron trifluoride.
Safety Information:
When using or handling 4 '-Fluoro-2-phenylacetophenone, pay attention to the following safety precautions:
-Contact: Avoid skin contact and inhalation, wear chemical protective gloves and breathing apparatus.
-Inhalation: If inhaled, seek medical attention immediately.
-Fire extinguishing: If a fire occurs, use a suitable fire extinguishing agent to extinguish, not water.
-Storage: should be stored in a dry, well-ventilated place, and away from fire and oxidizing agents.
-Waste disposal: Disposal in accordance with local regulations to avoid discharge into the environment.
Please note that this is only a general description of the 4 '-Fluoro-2-phenylacetophenone. The specific operation and use should follow the laboratory's safety regulations and operating guidelines. It is best to operate under the guidance of experienced chemical professionals.
Nature:
-Appearance: White to light yellow crystal or powder
-Molecular weight: 224.24g/mol
-Melting Point: 84-88°C
-Boiling point: 353°C
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane, slightly soluble in water.
Use:
-Chemical synthesis: 4 '-Fluoro-2-phenylacetophenone can be used as intermediates in organic synthesis, such as for the synthesis of drugs, pesticides and dyes.
-Research use: It is also commonly used in catalytic reactions and organic synthesis reactions in research.
Preparation Method:
The synthesis of 4 '-Fluoro-2-phenylacetophenone can be carried out by a variety of methods. A common method is to introduce fluorine atoms by reacting 2-phenylacetophenone with a fluorinating agent, such as hydrogen fluoride or boron trifluoride.
Safety Information:
When using or handling 4 '-Fluoro-2-phenylacetophenone, pay attention to the following safety precautions:
-Contact: Avoid skin contact and inhalation, wear chemical protective gloves and breathing apparatus.
-Inhalation: If inhaled, seek medical attention immediately.
-Fire extinguishing: If a fire occurs, use a suitable fire extinguishing agent to extinguish, not water.
-Storage: should be stored in a dry, well-ventilated place, and away from fire and oxidizing agents.
-Waste disposal: Disposal in accordance with local regulations to avoid discharge into the environment.
Please note that this is only a general description of the 4 '-Fluoro-2-phenylacetophenone. The specific operation and use should follow the laboratory's safety regulations and operating guidelines. It is best to operate under the guidance of experienced chemical professionals.
Last Update：2024-04-09 21:32:40
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Product Name: Atorvastatin Impurity 78 Visit Supplier Webpage Request for quotationCAS: 347-84-2
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Mobile: 86+15671228036
QQ: 2853786052
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Product Name: Benzyl 4-Fluorophenyl Ketone Visit Supplier Webpage Request for quotation
CAS: 347-84-2
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Mobile: 18021002903
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CAS: 347-84-2
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