4'-Hydroxychalcone
4'-HYDROXYCHALCONE
CAS: 2657-25-2
Molecular Formula: C15H12O2
4'-Hydroxychalcone - Names and Identifiers
| Name | 4'-HYDROXYCHALCONE |
| Synonyms | 4'-HYDROXYCHALCONE 4'-Hydroxychalcone 1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one 1-(p-Hydroxyphenyl)-3-phenyl-2-propene-1-one 2-Benzal-4'-hydroxyacetophenone2-Benzylidene-4'-hydroxyacetophenone |
| CAS | 2657-25-2 |
4'-Hydroxychalcone - Physico-chemical Properties
| Molecular Formula | C15H12O2 |
| Molar Mass | 224.25 |
| Density | 1.191±0.06 g/cm3(Predicted) |
| Melting Point | 174-178 °C |
| Boling Point | 419.6±45.0 °C(Predicted) |
| Solubility | Insoluble in water |
| Storage Condition | 2-8℃ |
| MDL | MFCD00016488 |
| Physical and Chemical Properties | Bioactive 4 '-hydroxy chalcone(P-Cinnamoylphenol), present in herbs, spices, and tea, is a licorice chalcone. It has a variety of biological activities, which can inhibit the activation of NF-κB pathway induced by TNF-α and activate BMP signaling pathway. |
4'-Hydroxychalcone - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37 - Wear suitable gloves. |
4'-Hydroxychalcone - Introduction
4 '-HYDROXYCHALCONE(4'-HYDROXYCHALCONE) is an organic compound with the formula C15H12O2. It is a yellow crystal or powder with a strong aromatic smell. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Yellow crystal or powder
-Solubility: Soluble in polar solvents such as ethanol, dimethyl sulfoxide and chloride solvents
-Melting point: about 180-182°C
-Aromatic degree: with strong aromatic smell
-chemical properties: is a kind of ketone compounds, can occur keto enol tautomerism reaction.
Use:
-Drugs: 4 '-HYDROXYCHALCONE has certain pharmacological activities and is widely used in drug research and development, such as as antioxidants and anti-inflammatory agents.
-Dyes: Can be used as raw materials for dyes, widely used in textiles, food and cosmetics and other fields.
-Optics: Due to its good fluorescence properties, it can be used to prepare fluorescent probes.
Preparation Method:
There are many preparation methods for 4 '-HYDROXYCHALCONE. One commonly used method is to synthesize by Aldol condensation reaction. First, benzaldehyde and acetone react under basic conditions to form 4 '-HYDROXYCHALCONE. After the reaction, the pure 4 '-HYDROXYCHALCONE product can be obtained by crystallization, filtration, washing and the like.
Safety Information:
- 4 '-HYDROXYCHALCONE is irritating and direct contact with skin and eyes should be avoided.
-Wear appropriate protective equipment such as gloves and goggles when in use.
-should be stored away from the fire and oxidant, stored in a cool, dry place.
-If it happens accidentally, immediately rinse the affected area with plenty of water and seek medical help.
Nature:
-Appearance: Yellow crystal or powder
-Solubility: Soluble in polar solvents such as ethanol, dimethyl sulfoxide and chloride solvents
-Melting point: about 180-182°C
-Aromatic degree: with strong aromatic smell
-chemical properties: is a kind of ketone compounds, can occur keto enol tautomerism reaction.
Use:
-Drugs: 4 '-HYDROXYCHALCONE has certain pharmacological activities and is widely used in drug research and development, such as as antioxidants and anti-inflammatory agents.
-Dyes: Can be used as raw materials for dyes, widely used in textiles, food and cosmetics and other fields.
-Optics: Due to its good fluorescence properties, it can be used to prepare fluorescent probes.
Preparation Method:
There are many preparation methods for 4 '-HYDROXYCHALCONE. One commonly used method is to synthesize by Aldol condensation reaction. First, benzaldehyde and acetone react under basic conditions to form 4 '-HYDROXYCHALCONE. After the reaction, the pure 4 '-HYDROXYCHALCONE product can be obtained by crystallization, filtration, washing and the like.
Safety Information:
- 4 '-HYDROXYCHALCONE is irritating and direct contact with skin and eyes should be avoided.
-Wear appropriate protective equipment such as gloves and goggles when in use.
-should be stored away from the fire and oxidant, stored in a cool, dry place.
-If it happens accidentally, immediately rinse the affected area with plenty of water and seek medical help.
Last Update：2024-04-09 21:04:16
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Multiple SpecificationsSpot supply
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