4,6-Dicloroindole-2-carboxylic acid

4,6-Dicloroindole-2-carboxylic acid - Names and Identifiers

Name	4,6-Dichloro-1H-indole-2-carboxylic acid
Synonyms	MDL 29951 4,6-Dicloroindole-2-Carboxylic 4,6-Dichloroindole-2-carboxylic 4,6-Dicloroindole-2-carboxylic acid 4,6-DICHLOROINDOLE-2-CARBOXYLIC ACID 6-Dichloro-1H-indole-2-carboxylic acid 4,6-DICHLORO-1H-INDOLE-2-CARBOXYLIC ACID 4,6-Dichloro-1H-indole-2-carboxylic acid 1H-Indole-2-carboxylicacid, 4,6-dichloro-
CAS	101861-63-6
InChI	InChI=1/C9H5Cl2NO2/c10-4-1-6(11)5-3-8(9(13)14)12-7(5)2-4/h1-3,12H,(H,13,14)

4,6-Dicloroindole-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C9H5Cl2NO2
Molar Mass	230.05
Density	1.663±0.06 g/cm3(Predicted)
Melting Point	238-239 °C
Boling Point	476.9±40.0 °C(Predicted)
Flash Point	242.2°C
Solubility	DMSO (Slightly, Methanol (Slightly, Heated)
Vapor Presure	6.64E-10mmHg at 25°C
Appearance	Solid
Color	Pale Beige
pKa	4.10±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.73

4,6-Dicloroindole-2-carboxylic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

4,6-Dicloroindole-2-carboxylic acid - Introduction

4,6-dichloroindole -2-carboxylic acid is an organic compound with the chemical formula C10H5Cl2NO2.

Nature:
1. Appearance: Colorless crystalline solid.
2. melting point: about 210-220 ℃.
3. Solubility: Soluble in organic solvents such as alcohol, ether, ketone and benzene, insoluble in water.

Use:
4,6-dichloroindole-2-carboxylic acid is widely used in the field of organic synthesis, commonly used in the synthesis of indole derivatives, bioactive compounds and drug molecules.

Preparation Method:
A common method for preparing 4,6-dichloroindole -2-carboxylic acid is by reacting 4,6-dichloroquinoline with formic acid. The reaction conditions may be carried out without solvent or under acidic or basic conditions.

Safety Information:
1. 4,6-dichloro indole -2-carboxylic acid may cause irritation and damage to human body. Attention should be paid to avoid touching skin, eyes and respiratory tract.
2. in use and storage, to maintain a well-ventilated environment.
3. use should wear appropriate protective gloves and eye protection equipment, avoid inhalation of gas or dust.
4. If exposed or inhaled, rinse immediately with water and seek medical help.

Last Update：2024-04-09 15:17:50