4,6-Difluoroindole C8H5F2N 153.13 - Names and Identifiers
Name | 4,6-Difluoroindole
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Synonyms | 4,6-DIFLUOROINDOLE 4,6-Difluoroindole 6-Difluoro-1H-indole 4,6-difluoro-1H-indole 4,6-Difluoro-1H-indole 1H-Indole, 4,6-difluoro- 1H-Indole,4,6-difluoro-(9CI) 4,6-Difluoroindole C8H5F2N 153.13
|
CAS | 199526-97-1
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InChI | InChI=1/C8H5F2N/c9-5-3-7(10)6-1-2-11-8(6)4-5/h1-4,11H |
4,6-Difluoroindole C8H5F2N 153.13 - Physico-chemical Properties
Molecular Formula | C8H5F2N
|
Molar Mass | 153.13 |
Density | 1.388±0.06 g/cm3(Predicted) |
Boling Point | 253.2±20.0 °C(Predicted) |
Flash Point | 106.919°C |
Solubility | Sparingly Soluble (0.062 g/L) (25°C), Calc. |
Vapor Presure | 0.03mmHg at 25°C |
pKa | 15.80±0.30(Predicted) |
Storage Condition | 2-8°C(protect from light) |
Sensitive | Air Sensitive |
Refractive Index | 1.616 |
4,6-Difluoroindole C8H5F2N 153.13 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Hazard Class | IRRITANT |
4,6-Difluoroindole C8H5F2N 153.13 - Introduction
4,6-difluoroindole (4,6-difluoroindole) is an organic compound with the chemical formula C8H5F2N. The following is an introduction to some of its properties, uses, methods and safety information:
Nature:
-Appearance: 4,6-difluoroindole is colorless to pale yellow crystal or powder.
-Melting point: About 70-74 ℃.
-Boiling point: about 330-335 ℃.
-Solubility: Soluble in some organic solvents, such as chloroform, dichloromethane and acetone.
Use:
- 4,6-difluoroindole is an important intermediate, which can be used in the synthesis of indole compounds in organic synthesis, such as indole derivatives, indoline, etc.
-It can also be used in the field of medicine as a precursor for potential bioactive molecules.
Method:
- 4,6-difluoroindole has many preparation methods, one of which is the synthesis of indole through fluorination. This can be achieved by reacting the indole with a fluorinating agent (e. G., trifluoroacetic anhydride, tetrafluoroboric acid, etc.) under appropriate conditions.
Safety Information:
-Due to the lack of data on the toxicity and danger of 4,6-difluoroindole, it is necessary to pay attention to safe operation during use and avoid contact with skin, inhalation or intake.
-Wear appropriate personal protective equipment such as chemical goggles, gloves and protective clothing when used.
-Store it in a dry, cool, well-ventilated place, away from fire and oxidants.
-For detailed safety information and operational guidelines, refer to the relevant chemical substance Safety Data Sheet (MSDS) or consult a professional for advice.
Last Update:2024-04-09 19:05:47