4,6-二氟吲哚-2-羧酸甲酯

4,6-二氟吲哚-2-羧酸甲酯 - Names and Identifiers

Name	1H-Indole-2-carboxylic acid, 4,6-difluoro-, methyl ester
Synonyms	methyl 4,6-difluoro-1H-indole-2-carboxylate 1H-Indole-2-carboxylic acid, 4,6-difluoro-, methyl ester
CAS	394222-99-2

4,6-二氟吲哚-2-羧酸甲酯 - Physico-chemical Properties

Molecular Formula	C10H7F2NO2
Molar Mass	211.16
Density	1.424±0.06 g/cm3(Predicted)
Boling Point	331.3±37.0 °C(Predicted)
pKa	13.77±0.30(Predicted)
Storage Condition	Room Temprature

4,6-二氟吲哚-2-羧酸甲酯 - Introduction

1H-Indole-2-carboxylic acid, 4,6-difluoro-, methyl ester is an organic compound with the chemical formula C10H6F2NO2. It is an indole derivative having two fluorine atoms and a carboxyl group substituted on the indole ring.

In terms of properties, 1H-Indole-2-carboxylic acid, 4,6-difluoro-, methyl ester is a solid with colorless or pale yellow crystals. Its melting point is about 63-65 degrees Celsius. This compound is stable at room temperature and does not readily decompose.

This compound has several applications in the medical field. Indole compounds are widely used in the synthesis and study of bioactive molecules. 1H-Indole-2-carboxylic acid, 4,6-difluoro-, methyl ester can be used as a pharmaceutical intermediate for the synthesis of biologically active compounds.

As for the preparation method, 1H-Indole-2-carboxylic acid, 4,6-difluoro-, methyl ester can be prepared by chemical synthesis. A common method is to react the indole-2-carboxylic acid with a fluorinating agent and then with methanol.

In terms of safety information, this compound should be handled with caution. Avoid contact with skin and eyes during operation, and wear appropriate protective gloves and glasses. In addition, it should be operated in a well-ventilated area and avoid inhaling its dust or vapor.

Last Update：2024-04-09 21:49:45