4-(3-FLUORO-PHENYL)-PIPERIDINE - Names and Identifiers
4-(3-FLUORO-PHENYL)-PIPERIDINE - Physico-chemical Properties
Molecular Formula | C11H14FN
|
Molar Mass | 179.23 |
Density | 1.048 |
Boling Point | 256℃ |
Flash Point | 108℃ |
Vapor Presure | 0.0163mmHg at 25°C |
pKa | 10.12±0.10(Predicted) |
Storage Condition | Room Temprature |
Refractive Index | 1.506 |
4-(3-FLUORO-PHENYL)-PIPERIDINE - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 52 - Harmful to aquatic organisms
|
Hazard Class | IRRITANT |
4-(3-FLUORO-PHENYL)-PIPERIDINE - Introduction
4-(3-fluorophenyl) piperidine is an organic compound with the chemical formula of C11H10FN, and the fluorine atom in the structure is located on the benzene ring. It is a colloidal solid, soluble in organic solvents such as ether and chloroform. The following are some properties and applications about 4-(3-fluorophenyl) piperidine:
Nature:
1. Appearance: white to off-white solid;
2. melting point: about 70-75 degrees Celsius;
3. Boiling point: about 260 degrees Celsius;
4. Density: about 1.15g/cm3.
Use:
1. Drug synthesis: 4-(3-fluorophenyl) piperidine is an important intermediate, which can be used to synthesize drugs and biological hormones, such as selective serotonin reuptake inhibitors and antidepressants;
2. pesticide synthesis: the compound can also be used in the synthesis of pesticides;
3. Other uses: 4-(3-fluorophenyl) piperidine can also be used as catalyst and reagent.
Preparation Method:
The preparation method of 4-(3-fluorophenyl) piperidine is more complicated, and generally needs to be synthesized by hydrogen chloride-catalyzed fluorination reaction.
Safety Information:
1. 4-(3-fluorophenyl) piperidine should be stored in a cool and dry place to avoid reaction with oxygen, moisture and acid;
2. use should wear appropriate protective gloves and eye protection equipment;
3. avoid inhalation of dust or contact with skin;
4. in the use or storage process should pay attention to comply with the relevant safety procedures and regulations.
Last Update:2024-04-09 02:00:40