4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL
CAS: 155957-43-0
Molecular Formula: C10H7FN2S
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL - Names and Identifiers
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL - Physico-chemical Properties
| Molecular Formula | C10H7FN2S |
| Molar Mass | 206.24 |
| Density | 1.30±0.1 g/cm3(Predicted) |
| Melting Point | 225° |
| Boling Point | 325.6±52.0 °C(Predicted) |
| pKa | 6.51±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD01315002 |
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL - Risk and Safety
| Hazard Class | IRRITANT |
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL - Introduction
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL is an organic compound with the chemical formula C10H7FN2S. The following is its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: 174-176 ° C
-Solubility: Soluble in organic solvents such as chloroform and dichloromethane, slightly soluble in water
Use:
- 4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL has certain biological activity and has potential use in drug research.
-It can also be used as an intermediate in organic synthesis and participate in the synthesis of other compounds.
Method:
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL is synthesized by the following reaction:
-Reaction of 4-fluorobenzaldehyde with thiourea under alkaline conditions to generate 4-(4-fluorophenyl) pyrimidine-2-thioaldehyde.
-Rereact 4-(4-fluorophenyl) pyrimidine-2-thioaldehyde with ammonium hydrogen sulfate or sulfoxide to generate 4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL.
Safety Information:
- 4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL is an organic compound, and attention should be paid to the safety measures when using it.
-It may have an irritating effect on the eyes, skin and respiratory system. Avoid contact with skin and eyes during operation, and ensure that it is used in a well-ventilated environment.
-Wear personal protective equipment such as goggles, gloves and respiratory protection when used.
Nature:
-Appearance: White crystalline solid
-Melting point: 174-176 ° C
-Solubility: Soluble in organic solvents such as chloroform and dichloromethane, slightly soluble in water
Use:
- 4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL has certain biological activity and has potential use in drug research.
-It can also be used as an intermediate in organic synthesis and participate in the synthesis of other compounds.
Method:
4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL is synthesized by the following reaction:
-Reaction of 4-fluorobenzaldehyde with thiourea under alkaline conditions to generate 4-(4-fluorophenyl) pyrimidine-2-thioaldehyde.
-Rereact 4-(4-fluorophenyl) pyrimidine-2-thioaldehyde with ammonium hydrogen sulfate or sulfoxide to generate 4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL.
Safety Information:
- 4-(4-FLUORO-PHENYL)-PYRIMIDINE-2-THIOL is an organic compound, and attention should be paid to the safety measures when using it.
-It may have an irritating effect on the eyes, skin and respiratory system. Avoid contact with skin and eyes during operation, and ensure that it is used in a well-ventilated environment.
-Wear personal protective equipment such as goggles, gloves and respiratory protection when used.
Last Update：2024-04-09 02:00:51
