4-(Pyridin-4-yl)phenyl boronic acid - Names and Identifiers
4-(Pyridin-4-yl)phenyl boronic acid - Physico-chemical Properties
Molecular Formula | C11H10BNO2
|
Molar Mass | 199.01 |
Density | 1.24±0.1 g/cm3(Predicted) |
Boling Point | 397.3±44.0 °C(Predicted) |
pKa | 7.62±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
4-(Pyridin-4-yl)phenyl boronic acid - Introduction
4-(4-pyridine) phenylboronic acid is an organic compound with the chemical formula C12H11BN2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
4-(4-Pyridine) phenylboronic acid is a powdered solid. It is stable at room temperature and has good solubility. It is soluble in organic solvents such as chloroform, methanol and acetonitrile.
Use:
4-(4-pyridyl) phenylboronic acid is an important intermediate in organic synthesis. It is widely used in coupling reactions in organic synthesis, especially in metal-catalyzed coupling reactions. It is often used as a ligand to form stable complexes with transition metals and participate in various catalytic reactions. It can also be used to synthesize drugs, organic molecular materials, etc.
Preparation Method:
The preparation of 4-(4-pyridine) phenylboronic acid is mainly completed by the coupling reaction of phenylboronic acid and 4-pyridine. The specific synthesis method includes the use of ligands, catalysts, etc., the reaction is carried out under appropriate solvent conditions and subsequent treatment, and finally the product is obtained.
Safety Information:
4-(4-pyridine) phenylboronic acid is generally a low-toxic compound under normal operating conditions, but it is still necessary to use appropriate safety equipment and operating methods in the laboratory for operation. In contact with this compound, avoid direct inhalation of its powder or solution, and avoid contact with skin and eyes. The working environment should be well ventilated. In the event of inadvertent entry or other unexpected conditions, seek medical advice immediately and provide information about the compound.
Last Update:2024-04-09 02:00:40