4-(Trifluoromethyl)phenylhydrazine

4-(Trifluoromethyl)phenylhydrazine - Names and Identifiers

Name	4-(Trifluoromethyl)-phenylhydrazine
Synonyms	4-(Trifluromethyl)phenylhydr 4-(Trifluoromethyl)phenylhydrazine 4-(Trifluoromethyl)-phenylhydrazine 4-(trifluoromethyl)benzoyl fluoride 1-[4-(Trifluoromethyl)phenyl]hydrazine 1-[4-(trifluoromethyl)phenyl]hydrazine Hydrazine, [4-(trifluoroMethyl)phenyl]- alpha,alpha,alpha-Trifluoro-p-tolylhydrazine 4-Hydrazinobenzotrifluoride, 1-Hydrazino-4-(trifluoromethyl)benzene 4-Hydrazinobenzotrifluoride, alpha,alpha,alpha-Trifluoro-p-tolylhydrazine
CAS	368-90-1
EINECS	609-305-9
InChI	InChI=1/C8H4F4O/c9-7(13)5-1-3-6(4-2-5)8(10,11)12/h1-4H

4-(Trifluoromethyl)phenylhydrazine - Physico-chemical Properties

Molecular Formula	C7H7F3N2
Molar Mass	176.14
Density	1.2773 (estimate)
Melting Point	63-65 °C (lit.)
Boling Point	118-122 °C/17 mmHg (lit.)
Flash Point	119-121°C/17mm
Water Solubility	Insoluble in water.
Vapor Presure	1mmHg at 25°C
Appearance	Solid
Color	Yellow to brown
BRN	743759
pKa	4.49±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.426
MDL	MFCD00042508

4-(Trifluoromethyl)phenylhydrazine - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes.
UN IDs	2811
WGK Germany	3
HS Code	29280000
Hazard Note	Irritant
Hazard Class	IRRITANT, TOXIC
Packing Group	III

4-(Trifluoromethyl)phenylhydrazine - Introduction

4-(Trifluoromethyl)-phenylhydrazine, also known as 4-(Trifluoromethyl)-phenylhydrazine, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
4-(Trifluoromethyl)-phenylhydrazine is a colorless to pale yellow crystal or liquid. Its chemical formula is C7H6F3N2 and its relative molecular mass is 184.14g/mol. The compound is stable at room temperature and pressure, but will burn when exposed to an ignition source. It is soluble in the solvent.

Use:
4-(Trifluoromethyl)-phenylhydrazine has certain application value in organic synthesis. It can be used as an active reagent for organic synthesis reactions, such as the synthesis of hydrazides and azoylation reactions. In addition, the compounds can also be used for the preparation of specific pharmaceutical compounds and biologically active molecules.

Preparation Method:
There are various methods for preparing 4-(Trifluoromethyl)-phenylhydrazine, but a common method is to react phenylhydrazine with a trifluoromethyl compound. The reaction process requires appropriate operating conditions and protective measures to ensure safety and avoid unnecessary losses.

Safety Information:
4-(Trifluoromethyl)-phenylhydrazine need to follow some safe operation regulations during operation. It may be irritating to the skin, eyes and respiratory tract, so wear appropriate personal protective equipment when handling. In addition, the compound has a certain toxicity, so it should be stored and handled properly. During use, attention should be paid to fire prevention and avoid contact with oxidants and other substances. If necessary, it should be operated under the guidance of professionals and master relevant first aid knowledge.

Last Update：2024-04-09 20:52:54