4-氯-1,3-二甲基-1氢-吡唑

4-氯-1,3-二甲基-1氢-吡唑 - Names and Identifiers

Name	4-Chloro-1,3-Dimethylpyrazole
Synonyms	Albb-004442 4-Chloro-1,3-Dimethy 4-Chloro-1,3-Dimethylpyrazole 4-CHLORO-1,3-DIMETHYLPYRAZOLE 4-chloro-1,3-dimethyl-1H-pyrazole 1H-Pyrazole, 4-chloro-1,3-dimethyl-
CAS	15878-44-1
InChI	InChI=1/C5H7ClN2/c1-4-5(6)3-8(2)7-4/h3H,1-2H3

4-氯-1,3-二甲基-1氢-吡唑 - Physico-chemical Properties

Molecular Formula	C5H7ClN2
Molar Mass	130.58
Density	1.21±0.1 g/cm3(Predicted)
Boling Point	50-56 °C(Press: 4 Torr)
Flash Point	65.595°C
Vapor Presure	0.984mmHg at 25°C
pKa	0.68±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.552

4-氯-1,3-二甲基-1氢-吡唑 - Risk and Safety

Hazard Class

IRRITANT

4-氯-1,3-二甲基-1氢-吡唑 - Introduction

4-Chloro-1,3-Dimethylpyrazole, also known as ClPy, is a compound with a specific structure. The following is an introduction to some of its properties, uses, methods and safety information:

Nature:
-Appearance: A colorless or light yellow liquid.
-Molecular formula: C6H8ClN.
-Molecular weight: 141.59.
-Boiling point: About 199 ° C.
-Density: about 1.104 g/ml.

Use:
-4-choro-1, 3-Dimethylpyrazole can be used as an intermediate in organic synthesis.
-It is used in the field of medicine for the preparation of drugs.
-It can also be used as a chemical reagent in research.

Method:
4-Chloro-1,3-Dimethylpyrazole can be synthesized by the following steps:
1. First, P-Toluic acid is reacted with nitroso acid to obtain p-nitrosyl acid.
2. Reacting p-nitrosotolubonic acid with dimethylamine to give 4-dimethylamino-1H-pyrazole.
3. Finally, 4-dimethylamino-1H-pyrazole is reacted with hydrogen chloride to obtain 4-Chloro-1,3-Dimethylpyrazole.

Safety Information:
- 4-Chloro-1,3-Dimethylpyrazole is irritating to the skin, eyes and respiratory tract, and personal protective measures should be paid attention to when using it.
-After contact with skin, rinse immediately with water.
-avoid inhalation of gas, mist or vapor, should be used in a well-ventilated place.
-When using, avoid contact with strong oxidants and strong acids.
-Storage should be sealed, and away from fire and high temperature environment.

Please note that chemical substances may have various properties and uses. Please read relevant materials carefully before specific use, and follow correct experimental operations and safety regulations.

Last Update：2024-04-09 19:05:46