4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid
SR 11237
CAS: 146670-40-8
Molecular Formula: C24H28O4
4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid - Names and Identifiers
4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid - Physico-chemical Properties
| Molecular Formula | C24H28O4 |
| Molar Mass | 380.48 |
| Solubility | DMSO: >28mg/mL (warmed) |
| Appearance | powder |
| Color | white to off-white |
| Storage Condition | Store at -20°C |
| In vitro study | Using nuclear receptor co-transfection assays in COS-1 cells, that SR11237 is effective at transactivating a chloramphenicol acetyltransferase reporter gene through RXRs but not retinoic acid receptors. |
| In vivo study | SR11237 (BMS-649) (25 mg/kg; i.p.; daily from post-natal days 5 to 15) causes irregular ossification and premature closure of the growth plate. Animal Model: Sprague-Dawley rats Dosage: 25 mg/kg Administration: I.p.; daily from post-natal days 5 to 15 Result: Caused disturbed ossification and bone morphology in rats, including premature growth plate closure and infiltration of ossified tissue through the central epiphysis. |
4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid - Risk and Safety
| WGK Germany | 3 |
4-(2-(5,5,8,8-tetraMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)-1,3-dioxolan-2-yl)benzoic acid - Introduction
SR 11237 is an organic compound with the chemical formula C8H8ClNO2S. It is a colorless crystalline solid with a strong odor. The SR 11237 melts at normal temperature and is soluble in organic solvents such as ethanol and methylene chloride.
SR 11237 has a certain application in the field of medicine. It has certain antibacterial activity and can be used to prepare antibacterial drugs. In addition, the study found that SR 11237 also has antimalarial activity, and is expected to be used for the treatment of malaria.
The method of preparing SR 11237 is to synthesize through organic synthetic chemical reactions. The specific preparation method can be selected according to the specific literature and laboratory conditions.
When using and handling SR 11237, you need to pay attention to some safety matters. It is an organic compound with certain toxicity. Wear suitable protective gloves, glasses and protective clothing during handling and storage. When disposing of waste, it is necessary to dispose of it in accordance with relevant environmental protection regulations. In addition, SR 11237 should be stored in a dry, cool place, away from fire and oxidizing agents. Prior to use and handling, the relevant safety guidelines and operating procedures should be understood and followed in detail.
SR 11237 has a certain application in the field of medicine. It has certain antibacterial activity and can be used to prepare antibacterial drugs. In addition, the study found that SR 11237 also has antimalarial activity, and is expected to be used for the treatment of malaria.
The method of preparing SR 11237 is to synthesize through organic synthetic chemical reactions. The specific preparation method can be selected according to the specific literature and laboratory conditions.
When using and handling SR 11237, you need to pay attention to some safety matters. It is an organic compound with certain toxicity. Wear suitable protective gloves, glasses and protective clothing during handling and storage. When disposing of waste, it is necessary to dispose of it in accordance with relevant environmental protection regulations. In addition, SR 11237 should be stored in a dry, cool place, away from fire and oxidizing agents. Prior to use and handling, the relevant safety guidelines and operating procedures should be understood and followed in detail.
Last Update：2024-04-09 20:52:54
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Product Name: SR 11237 Visit Supplier Webpage Request for quotation
CAS: 146670-40-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 146670-40-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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