4-(2-Chloroethylsulfonyl)butanoic acid
4-(2-Chloroethylsulfonyl)butanoic acid
CAS: 75055-25-3
Molecular Formula: C6H11ClO4S
4-(2-Chloroethylsulfonyl)butanoic acid - Names and Identifiers
| Name | 4-(2-Chloroethylsulfonyl)butanoic acid |
| Synonyms | 4-(2-CHLOROETHYLSULFONYL)BUTANOIC ACID 4-(2-Chloroethylsulfonyl)butanoic acid 4-[(2-Chloroethyl)sulfonyl]butanoic acid butanoic acid, 4-[(2-chloroethyl)sulfonyl]- |
| CAS | 75055-25-3 |
| InChI | InChI=1/C6H11ClO4S/c7-3-5-12(10,11)4-1-2-6(8)9/h1-5H2,(H,8,9) |
4-(2-Chloroethylsulfonyl)butanoic acid - Physico-chemical Properties
| Molecular Formula | C6H11ClO4S |
| Molar Mass | 214.67 |
| Density | 1.388g/cm3 |
| Melting Point | 98 °C |
| Boling Point | 462.8°C at 760 mmHg |
| Flash Point | 233.7°C |
| Vapor Presure | 7.56E-10mmHg at 25°C |
| Refractive Index | 1.495 |
4-(2-Chloroethylsulfonyl)butanoic acid - Introduction
4-(2-Chloroethylsulfonyl)butanoic acid is an organic compound with the chemical formula C8H15ClO4S. It is a colorless crystal, insoluble in water, soluble in organic solvents. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: colorless crystal
-Molecular weight: 235.72g/mol
-melting point: 67-70 ℃
-Boiling point: 321 ℃
-Density: 1.29g/cm3
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol, methanol and dichloromethane
Use:
4-(2-Chloroethylsulfonyl)butanoic acid is mainly used in the field of organic synthesis as an important intermediate. It can be involved in the synthesis of various organic compounds, such as drugs, dyes and pesticides. Specific applications include the synthesis of novel anticancer drugs, antiviral drugs, and drugs for regulating hormone secretion.
Preparation Method:
The preparation of 4-(2-Chloroethylsulfonyl)butanoic acid is generally carried out by the following steps:
1. 4-hexanol and p-toluenesulfonic acid were reacted under acid catalysis to obtain hexyl p-toluenesulfonate.
2. hexyl p-toluenesulfonate is heated to react with chloroethanol under alkaline conditions to obtain 4-(2-chloroethylsulfo) butyric acid.
3.4-(2-chloroethylsulfo) butyric acid is reacted with alkali to obtain the final product 4-(2-Chloroethylsulfonyl)butanoic acid.
Safety Information:
4-(2-Chloroethylsulfonyl)butanoic acid is an organic compound and should be handled with caution. The following is a brief description of its security information:
-Eye contact: avoid eye contact, if contact, please immediately rinse with plenty of water, and seek medical help.
-skin contact: to prevent skin exposure, wear protective gloves, protective clothing and other personal protective equipment.
-Inhalation: Avoid inhaling gases, fumes, vapors or sprays. If inhaled, move to fresh air.
-Follow good laboratory safety practices and properly store and dispose of waste.
-For detailed safety information, please refer to the relevant Material Safety Data Sheet.
Nature:
-Appearance: colorless crystal
-Molecular weight: 235.72g/mol
-melting point: 67-70 ℃
-Boiling point: 321 ℃
-Density: 1.29g/cm3
-Solubility: Insoluble in water, soluble in organic solvents such as ethanol, methanol and dichloromethane
Use:
4-(2-Chloroethylsulfonyl)butanoic acid is mainly used in the field of organic synthesis as an important intermediate. It can be involved in the synthesis of various organic compounds, such as drugs, dyes and pesticides. Specific applications include the synthesis of novel anticancer drugs, antiviral drugs, and drugs for regulating hormone secretion.
Preparation Method:
The preparation of 4-(2-Chloroethylsulfonyl)butanoic acid is generally carried out by the following steps:
1. 4-hexanol and p-toluenesulfonic acid were reacted under acid catalysis to obtain hexyl p-toluenesulfonate.
2. hexyl p-toluenesulfonate is heated to react with chloroethanol under alkaline conditions to obtain 4-(2-chloroethylsulfo) butyric acid.
3.4-(2-chloroethylsulfo) butyric acid is reacted with alkali to obtain the final product 4-(2-Chloroethylsulfonyl)butanoic acid.
Safety Information:
4-(2-Chloroethylsulfonyl)butanoic acid is an organic compound and should be handled with caution. The following is a brief description of its security information:
-Eye contact: avoid eye contact, if contact, please immediately rinse with plenty of water, and seek medical help.
-skin contact: to prevent skin exposure, wear protective gloves, protective clothing and other personal protective equipment.
-Inhalation: Avoid inhaling gases, fumes, vapors or sprays. If inhaled, move to fresh air.
-Follow good laboratory safety practices and properly store and dispose of waste.
-For detailed safety information, please refer to the relevant Material Safety Data Sheet.
Last Update：2024-04-09 20:02:46
