4-(2H-TETRAZOL-5-YL)-BENZOIC ACID
4-(1H-Tetrazol-5-yl)benzoic acid
CAS: 34114-12-0
Molecular Formula: C8H6N4O2
4-(2H-TETRAZOL-5-YL)-BENZOIC ACID - Names and Identifiers
4-(2H-TETRAZOL-5-YL)-BENZOIC ACID - Physico-chemical Properties
| Molecular Formula | C8H6N4O2 |
| Molar Mass | 190.16 |
| Density | 1.518 |
| Melting Point | 248-250℃ |
| Boling Point | 467.5±47.0 °C(Predicted) |
| Flash Point | 83.1°C |
| Vapor Presure | 0.401mmHg at 25°C |
| pKa | 3?+-.0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| MDL | MFCD06345720 |
4-(2H-TETRAZOL-5-YL)-BENZOIC ACID - Risk and Safety
| Risk Codes | 22 - Harmful if swallowed |
| Hazard Class | IRRITANT |
4-(2H-TETRAZOL-5-YL)-BENZOIC ACID - Reference Information
| Use | 5-(4-phenyl formate)-1H-tetrazole is an organic intermediate, which can be prepared from 4-cyanobenzoic acid. There are reports that it can be used to prepare autocrine motility factor inhibitors. |
| preparation | sodium azide (0.11mol, 7.15g) and ammonium chloride (0.11mol, 5.88g) are dissolved in 100 mL of anhydrous DMF. Stir the solution at room temperature for 30 minutes. 4-cyanobenzoic acid (0.1mol,14.71g) was added to the solution under stirring. The mixture was then refluxed at 120°C for 18-20 hours under stirring. After cooling to room temperature, the solution was acidified with 200mL of hydrochloric acid ml(1M) solution under stirring. The white precipitate formed by filtration was washed with a continuous aliquent of distilled water (3 x 25 mL). The resulting product was recrystallized in anhydrous acetone (yield 90%,13.23g). |
Last Update：2024-04-09 21:04:16
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Product Name: 4-(1H-Tetrazol-5-yl)Benzoic Acid Visit Supplier Webpage Request for quotationCAS: 34114-12-0
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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