4-(BROMOMETHYL)PYRIDINE, HYDROBROMIDE - Names and Identifiers
4-(BROMOMETHYL)PYRIDINE, HYDROBROMIDE - Physico-chemical Properties
Molecular Formula | C6H7Br2N
|
Molar Mass | 252.93 |
Melting Point | 189-192°C(lit.) |
Color | White powder |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
MDL | MFCD01863545 |
4-(BROMOMETHYL)PYRIDINE, HYDROBROMIDE - Risk and Safety
Hazard Symbols | C - Corrosive
|
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 3261 8/PG 2 |
WGK Germany | 3 |
HS Code | 29333990 |
Hazard Class | 8 |
Packing Group | Ⅱ |
4-(BROMOMETHYL)PYRIDINE, HYDROBROMIDE - Introduction
4-(bromomethyl)pyridine hydrobromide is an organic compound with a chemical formula of C6H6Br2N2 and a relative molecular mass of 252.93g/mol. It is a colorless crystal or white powder that slowly dissolves in a solvent. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: colorless crystal or white powder
-Solubility: Dissolved in water and organic solvents such as methanol, ethanol and chloroform
-Melting point: about 125-130 ℃
-pKa value of hydrochloride: about 4.9 (indicating that it is a weak acid)
Use:
4-(bromomethyl)pyridine hydrobromide is often used as a donor for bromomethyl groups in organic synthesis, and is mainly used for the synthesis of various organic compounds containing bromomethyl groups. It can also be used as an intermediate in the field of medicine for the synthesis of drugs, such as antibacterial drugs and anticancer drugs.
Preparation Method:
4-(bromomethyl)pyridine hydrobromide is usually prepared by reacting 4-pyridylmethanol with sodium hypobromite (NaBrO) to obtain the corresponding bromide, and then reacting with hydrobromic acid to obtain 4-(bromomethyl)pyridine hydrobromide.
Safety Information:
- 4-(bromomethyl)pyridine hydrobromide are irritating and may cause eye and skin damage, so proper safety precautions should be taken when handling, such as wearing gloves and goggles.
-It should be stored in a cool, dry place and away from fire and oxidizing agents.
-Please follow the laboratory and chemical safety procedures, and check the chemical safety data form before use.
Last Update:2024-04-09 20:49:11