4-(Pyridin-3-yl)benzoic acid
4-Pyrid-4-ylbenzoic acid
CAS: 4385-76-6
Molecular Formula: C12H9NO2
4-(Pyridin-3-yl)benzoic acid - Names and Identifiers
| Name | 4-Pyrid-4-ylbenzoic acid |
| Synonyms | 4-Pyrid-4-ylbenzoic acid 4-pyrid-3-ylbenzoic acid 4-PYRID-4-YLBENZOIC ACID 4-PYRID-3-YLBENZOIC ACID 4'-PYRIDYL-4-BENZOIC ACID 4-(3-PYRIDYL)BENZOIC ACID 4-(3-PYRIDINYL)BENZOIC ACID 4-(4-CARBOXYPHENYL)PYRIDINE 4-PYRIDIN-3-YL-BENZOIC ACID 4-PYRIDIN-4-YL-BENZOIC ACID 4-(pyridin-4-yl)benzoic acid 4-(Pyridin-3-yl)benzoic acid Benzoic acid, 4-(3-pyridinyl)- |
| CAS | 4385-76-6 |
| InChI | InChI=1/C12H9NO2/c14-12(15)11-3-1-9(2-4-11)10-5-7-13-8-6-10/h1-8H,(H,14,15) |
4-(Pyridin-3-yl)benzoic acid - Physico-chemical Properties
| Molecular Formula | C12H9NO2 |
| Molar Mass | 199.21 |
| Density | 1.241±0.06 g/cm3(Predicted) |
| Melting Point | >300°C |
| Boling Point | 384.3±25.0 °C(Predicted) |
| Flash Point | 186.2°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 1.36E-06mmHg at 25°C |
| pKa | 3?+-.0.10(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.613 |
| MDL | MFCD04114574 |
4-(Pyridin-3-yl)benzoic acid - Risk and Safety
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. S37 - Wear suitable gloves. |
| HS Code | 29333990 |
| Hazard Class | IRRITANT |
4-(Pyridin-3-yl)benzoic acid - Introduction
4-Pyrid-4-ylbenzoic acid is a chemical substance that contains a benzoic acid group and a pyridine group in its chemical structure. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 4-Pyrid-4-ylbenzoic acid is a colorless to pale yellow crystalline powder.
-Solubility: It is slightly soluble in water and soluble in some organic solvents, such as alcohols and ethers.
-Chemical properties: It is an acidic compound that can neutralize with alkalis.
Use:
-Chemical synthesis: 4-Pyrid-4-ylbenzoic acid is commonly used as a reagent and intermediate in organic synthesis.
-Target drug design: It can be used in drug research and target drug design, as the basic structure of drugs or the building unit of chiral molecules.
Preparation Method:
The preparation of 4-Pyrid-4-ylbenzoic acid is usually carried out by the following steps:
1. Reaction of pyridine with bromotoluene to give 4-bromo-tolylpyridine (4-Bromomethylpyridine).
2. 4-bromotolyl pyridine reacts with benzoic acid to obtain 4-Pyrid-4-ylbenzoic acid through substitution reaction.
Safety Information:
- 4-Pyrid-4-ylbenzoic acid theoretically does not have a significant acute toxic effect on humans.
-However, any chemical should be used according to correct operating procedures, avoid inhalation, contact with skin and eyes, and avoid ingestion.
-Observe safe operating procedures during use, storage and disposal, and pay attention to the use of personal protective equipment (such as laboratory gloves, goggles and laboratory coats).
-Detailed safety information and toxicity data for 4-Pyrid-4-ylbenzoic acid can be obtained through relevant chemical databases or safety data sheets provided by suppliers.
Nature:
-Appearance: 4-Pyrid-4-ylbenzoic acid is a colorless to pale yellow crystalline powder.
-Solubility: It is slightly soluble in water and soluble in some organic solvents, such as alcohols and ethers.
-Chemical properties: It is an acidic compound that can neutralize with alkalis.
Use:
-Chemical synthesis: 4-Pyrid-4-ylbenzoic acid is commonly used as a reagent and intermediate in organic synthesis.
-Target drug design: It can be used in drug research and target drug design, as the basic structure of drugs or the building unit of chiral molecules.
Preparation Method:
The preparation of 4-Pyrid-4-ylbenzoic acid is usually carried out by the following steps:
1. Reaction of pyridine with bromotoluene to give 4-bromo-tolylpyridine (4-Bromomethylpyridine).
2. 4-bromotolyl pyridine reacts with benzoic acid to obtain 4-Pyrid-4-ylbenzoic acid through substitution reaction.
Safety Information:
- 4-Pyrid-4-ylbenzoic acid theoretically does not have a significant acute toxic effect on humans.
-However, any chemical should be used according to correct operating procedures, avoid inhalation, contact with skin and eyes, and avoid ingestion.
-Observe safe operating procedures during use, storage and disposal, and pay attention to the use of personal protective equipment (such as laboratory gloves, goggles and laboratory coats).
-Detailed safety information and toxicity data for 4-Pyrid-4-ylbenzoic acid can be obtained through relevant chemical databases or safety data sheets provided by suppliers.
Last Update：2024-04-09 20:45:29
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Product Name: 4-(4-Pyridyl)Benzoic Acid Visit Supplier Webpage Request for quotationCAS: 4385-76-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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