4-ACETOXYPHENYLBORONIC ACID, PINACOL ESTER - Names and Identifiers
Name | 4-Acetoxyphenylboronic acid pinacol ester
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Synonyms | 4-Acetoxyphenylboronic acid pinacol ester 4-ACETOXYPHENYLBORONIC ACID, PINACOL ESTER 2-[4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetate 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenylacetate 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl acetate 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL ACETATE 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetate
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CAS | 480424-70-2
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4-ACETOXYPHENYLBORONIC ACID, PINACOL ESTER - Physico-chemical Properties
Molecular Formula | C14H19BO4
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Molar Mass | 262.11 |
Density | 1.08±0.1 g/cm3(Predicted) |
Melting Point | 67-71 °C (lit.) |
Boling Point | 351.9±25.0 °C(Predicted) |
Appearance | Powder |
Color | white to yellow |
Storage Condition | Inert atmosphere,Room Temperature |
MDL | MFCD03453060 |
4-ACETOXYPHENYLBORONIC ACID, PINACOL ESTER - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
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WGK Germany | 3 |
HS Code | 29189900 |
4-ACETOXYPHENYLBORONIC ACID, PINACOL ESTER - Introduction
4-Acetoxyphenylboronic acid pinacol ester is an organic compound with the chemical formula C14H17BO4.
Nature:
-Appearance: Colorless to light yellow solid
-Melting point: about 70-74°C
-Stability: stable at room temperature, but should avoid direct sunlight and moisture
-Solubility: Soluble in common organic solvents such as methanol, ethanol, dichloromethane
Use:
-As a reagent in organic synthesis: it can react with halogenated aromatic hydrocarbons to generate acetoxyphenylboronic acid, which can be used to construct aryl boronic acid derivatives.
-In drug research: It can be used as an intermediate for the synthesis of drugs or active compounds.
-In materials science: it can be used to prepare polymers, ligands, catalysts, etc.
Preparation Method:
A commonly used preparation method is to react 4-hydroxyphenylboronic acid with the main compound 2,3-dimethyl -1,2-butanediol to generate 4-hydroxyphenylboronic acid. This product is then reacted with acetic anhydride to produce the final 4-acetoxyphenylboronic acid pinacol ester.
Safety Information:
- 4-Acetoxyphenylboronic acid pinacol ester has less specific safety data, but according to the chemical structure and conventional chemical knowledge, inhalation, intake and skin contact should generally be avoided.
-During use, it is necessary to ensure good ventilation conditions to avoid dust or gas.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
-Read the product safety instructions before use and use personal protective equipment (such as gloves, glasses, etc.) to ensure safety. It is best used in a chemical laboratory or under the guidance of a professional.
Last Update:2024-04-09 21:32:41