4-BROMONICOTINIC ACID
4-Bromonicotinic acid
CAS: 15366-62-8
Molecular Formula: C6H4BrNO2
4-BROMONICOTINIC ACID - Names and Identifiers
| Name | 4-Bromonicotinic acid |
| Synonyms | 4-Bromnicotins?ure 4-Bromonicotinic acid 4-BROMONICOTINIC ACID 3-acid-4-bromopyridine acide 4-bromonicotinique 4-BROMO-3-PYRIDINECARBOXYLIC ACID 4-Bromo-3-pyridine carboxlic acid 4-BROMOPYRIDINE-3-CARBOXYLIC ACID 4-Bromopyridine-3-carboxylic acid 3-Pyridinecarboxylic acid, 4-bromo- Acide 4-bromopyridine-3-carboxylique |
| CAS | 15366-62-8 |
| InChI | InChI=1/C6H4BrNO2/c7-5-1-2-8-3-4(5)6(9)10/h1-3H,(H,9,10) |
| InChIKey | CZLOEKRJQIAKFI-UHFFFAOYSA-N |
4-BROMONICOTINIC ACID - Physico-chemical Properties
| Molecular Formula | C6H4BrNO2 |
| Molar Mass | 202.01 |
| Density | 1.813±0.06 g/cm3(Predicted) |
| Melting Point | 118-134℃ |
| Boling Point | 334.5±27.0 °C(Predicted) |
| Flash Point | 156.1°C |
| Vapor Presure | 5.02E-05mmHg at 25°C |
| Appearance | Solid |
| Color | Pale brown to dark brown |
| pKa | 0.85±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | 1.616 |
4-BROMONICOTINIC ACID - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
| WGK Germany | 3 |
| Hazard Class | IRRITANT, KEEP COLD, |
4-BROMONICOTINIC ACID - Reference Information
| Introduction | nicotinic acid was first isolated from rice bran and yeast. Nicotinic acid can be used as food, feed additives. Recent studies have also demonstrated that nicotinic acid has a significant effect on lowering blood esters. In particular, the effect of reducing blood triglycerides is better, and it also has a role in reducing the level of cholesterol in the blood. Among them, 4-bromo nicotinic acid is an important pharmaceutical intermediate, which has a wide range of uses in the field of medicine. |
| Use | 4-bromo nicotinic acid and related derivatives have been shown to inhibit Streptococcus, Staphylococcus aureus, Escherichia coli, lactic acid bacteria, etc. 4-bromonicotinic acid inhibits the growth of both Gram-positive and gram-negative bacteria, but its inhibition can be competitively reversed by nicotinic acid. The main role of 4-bromonicotinic acid inhibits the synthesis of coenzyme parent, such as nicotinic acid, nicotinamide, nicotinamide riboside; Part of nicotinamide riboside synthesis coenzyme is inhibited, but the absorption of coenzyme is not affected, and the absorption amount is 2~3UG/mg.. |
Last Update：2024-04-09 20:49:11
