4-Bromo-2-fluoro-3-methoxybenzoic acid

4-Bromo-2-fluoro-3-methoxybenzoic acid - Names and Identifiers

Name	4-BROMO-2-FLUORO-3-METHOXY-BENZOIC ACID
Synonyms	4-Bromo-2-fluoro-3-methoxybenzoic acid 4-BROMO-2-FLUORO-3-METHOXY-BENZOIC ACID benzoic acid, 4-bromo-2-fluoro-3-methoxy- Benzoic acid, 4-bromo-2-fluoro-3-methoxy-
CAS	194804-92-7
InChI	InChI=1/C8H6BrFO3/c1-13-7-5(9)3-2-4(6(7)10)8(11)12/h2-3H,1H3,(H,11,12)

4-Bromo-2-fluoro-3-methoxybenzoic acid - Physico-chemical Properties

Molecular Formula	C8H6BrFO3
Molar Mass	249.03
Density	1.701±0.06 g/cm3(Predicted)
Melting Point	168-170 °C
Boling Point	331.0±42.0 °C(Predicted)
Flash Point	154°C
Vapor Presure	6.41E-05mmHg at 25°C
pKa	2.92±0.10(Predicted)
Sensitive	Light Sensitive/Air Sensitive
Refractive Index	1.563
Physical and Chemical Properties	Sensitivity: Light Sensitive/Air Sensitive

4-Bromo-2-fluoro-3-methoxybenzoic acid - Risk and Safety

Risk Codes

22 - Harmful if swallowed

4-Bromo-2-fluoro-3-methoxybenzoic acid - Introduction

Nature:
-Appearance: ACID is colorless or yellowish crystal powder.
-Melting point: About 168-172 ° C.
-Solubility: Soluble in organic solvents such as chloroform, dichloromethane and ethanol.

Use:
-must ACID can be used as an intermediate in organic synthesis.
-It has certain application value in the field of drug synthesis.

Method:
-A common preparation method is to react 3-methoxy-4-bromophenol with sodium fluoride to generate 4-bromo-3-fluorobenzoic acid. Then, it is treated in methanol by a formic ACID esterification reaction under an ACID catalyst to obtain a metal ACID.

Safety Information:
-the specific toxicity and carcinogenicity of ACID have not been fully evaluated, please follow the relevant laboratory safety procedures.
-Avoid contact with skin, eyes and respiratory tract during use, storage and handling.
-Wear appropriate personal protective equipment such as gloves, glasses and masks during operation.

Last Update：2024-04-09 02:00:43