4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene

4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene - Names and Identifiers

Name	4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE
Synonyms	TIMTEC-BB SBB006655 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL ISOCYANATE 4-chloro-1-isocyanato-2-(trifluoromethyl)benzene 4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene Benzene, 4-chloro-1-isocyanato-2-(trifluoromethyl)-
CAS	16588-69-5
EINECS	625-436-4
InChI	InChI=1/C8H3ClF3NO/c9-5-1-2-7(13-4-14)6(3-5)8(10,11)12/h1-3H

4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene - Physico-chemical Properties

Molecular Formula	C8H3ClF3NO
Molar Mass	221.56
Density	1.467g/mLat 25°C(lit.)
Boling Point	64-64.5°C0.5mm Hg(lit.)
Flash Point	202°F
Vapor Presure	0.0263mmHg at 25°C
Appearance	Transparent colorless liquid
BRN	2214336
Storage Condition	Room Temprature
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.501(lit.)
MDL	MFCD00013873
Physical and Chemical Properties	Sensitivity: motion Sensitive WGK Germany:3

4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S7 - Keep container tightly closed. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	UN 2206 6.1/PG 3
WGK Germany	3
HS Code	29291090
Hazard Note	Harmful
Hazard Class	6.1
Packing Group	III

4-Chloro-1-isocyanato-2-(trifluoromethyl)benzene - Introduction

4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL isocyyanate (also known as "4-CHLORO-2, 2,2-trifluoroacetyl formate") is an organic compound with the chemical formula C4ClF3NCO. Here are some information about its nature, use, formulation and safety:

Nature:
-Appearance: colorless liquid
-Density: 1.58 g/mL
-Boiling point: 78-80 ° C
-Molecular weight: 183.5g/mol
-Flammability: Flammable
-Solubility: Soluble in many organic solvents, such as alcohols and ethers

Use:
4-choro-2-(TRIFLUOROMETHYL) phenol ISOCYANATE has a wide range of applications in organic synthesis and is commonly used in the following areas:
-Preparation of drugs: used as pharmaceutical intermediates, especially for the synthesis of antibacterial drugs and pesticides.
-Polymerization: as a monomer to participate in the synthesis of polymers, such as polyurethane and polyvinyl alcohol.
-Surface treatment agent: used to improve the surface properties of materials, such as coatings and coatings.

Method:
4-choro-2-(TRIFLUOROMETHYL)PHENYL isocyyanate can be prepared:
-Reaction of 2,2, 2-trifluoroacetyl chloride (C2F3ClO) and TRIFLUOROMETHYL ISOCYANATE (C2F3NCO) to produce 4-CHLORO-2-(TRIFLUOROMETHYL) phenol ISOCYANATE.

Safety Information:
-4-choro-2-(TRIFLUOROMETHYL) phenol ISOCYANATE is irritating and corrosive, and requires appropriate protective measures, such as gloves, protective glasses and protective masks.
-Avoid breathing vapors, contact with skin, eyes and clothing. In the operation should pay attention to good ventilation conditions.
-In the event of misuse or exposure, seek medical help immediately and provide the packaging or label to the doctor for an accurate diagnosis.
-4-choro-2-(TRIFLUOROMETHYL) phenol ISOCYANATE should be stored in a closed container, away from fire and high temperature.

Please note that this compound needs to be used with experience and appropriate equipment to ensure safety and correct operation.

Last Update：2024-04-09 15:17:53