4-Chloro-3-cyanophenylboronic acid

4-Chloro-3-cyanophenylboronic acid - Names and Identifiers

Name	4-Chloro-3-cyanophenylboronic acid
Synonyms	5-Borono-2-chlorobenzonitrile 4-CHLORO-3-CYANOPHENYLBORONIC ACID 4-Chloro-3-cyanophenylboronic acid 4-CHLORO-3-CYANOBENZENEBORONIC ACID 4-Chloro-3-cyanobenzeneboronic acid Boronic acid, B-(4-chloro-3-cyanophenyl)- 4-Chloro-3-cyanophenylboronic acid, 4-Chloro-3-cyanobenzeneboronic acid 4-Chloro-3-cyanobenzeneboronic acid(contains varying amounts of Anhydride)
CAS	871332-95-5
InChI	InChI=1/C7H5BClNO2/c9-7-2-1-6(8(11)12)3-5(7)4-10/h1-3,11-12H

4-Chloro-3-cyanophenylboronic acid - Physico-chemical Properties

Molecular Formula	C7H5BClNO2
Molar Mass	181.38
Density	1.41±0.1 g/cm3(Predicted)
Melting Point	300-304
Boling Point	380.4±52.0 °C(Predicted)
Flash Point	183.9°C
Vapor Presure	1.83E-06mmHg at 25°C
Appearance	Solid
Color	White to yellow
pKa	6.98±0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.58
MDL	MFCD08056360

4-Chloro-3-cyanophenylboronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S60 - This material and its container must be disposed of as hazardous waste. S36/37 - Wear suitable protective clothing and gloves.
UN IDs	3439
HS Code	29319090
Hazard Note	Irritant/Keep Cold
Hazard Class	6.1
Packing Group	Ⅲ

4-Chloro-3-cyanophenylboronic acid - Introduction

Acid is an organic compound with the chemical formula C7H5BClNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: acid is white crystalline powder.
-Melting point: about 170-175°C.
-Solubility: Soluble in common organic solvents such as chloroform, disulfide and dimethyl sulfoxide, slightly soluble in water.

Use:
-acid is an important organic synthesis intermediate, commonly used in organic synthesis reactions. It can be used as a synthetic reagent for aromatic compounds and their derivatives.

Preparation Method:
-and acid is usually prepared by the following steps:
1. First, 4-chloro -3-cyanoiodobenzene is reacted with sodium hydroxide to generate the corresponding phenolate compound.
2. Then, the phenolate is reacted with boric acid and a catalyst to form a phenol acid.

Safety Information:
-the specific toxicity information of acid may be limited, so it should be handled with caution during use.
-Avoid skin contact and eye contact to avoid irritation. In case of contact, rinse immediately with plenty of water.
-Wear appropriate protective equipment such as lab gloves, goggles and lab coats during operation.
-The operation should be carried out in a well-ventilated place to avoid inhaling the powder or the gas generated.
-Storage should be sealed and kept away from fire and oxidizing agents.

Please note that the information provided above is for reference only. Please follow relevant safety practices when using and handling chemicals.

Last Update：2024-04-10 22:29:15