4-Chloro-4'-hydroxybenzophenone

4-Chloro-4'-hydroxybenzophenone - Names and Identifiers

Name	4-Chloro-4'-hydroxybenzophenone
Synonyms	LABOTEST-BB LT00248477 4-p-Chlorobenzoylphenol 4-(4-CHLOROBENZOYL)PHENOL 4-Chloro-4-Hydroxybenzophenone 4-Chloro-4'-hydroxybenzophenon 4-Chloro-4'-hydroxybenzophenone 4-hydroxy-4'-chloro-benophenone 4-chloro-4'-hydroxy benzophenone 4-(4-Chlorobenzoyl)-4-Hydroxypiperidine (4-chlorophenyl)(4-hydroxyphenyl)methanone (4-Chlorophenyl)(4-hydroxyphenyl)-Methanone 4-Chloro-4'-Hydroxybenzophenone 4-Hydroxy-4'-Chlorobenzophenone
CAS	42019-78-3
EINECS	255-627-4
InChI	InChI=1/C13H9ClO2/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(15)8-4-10/h1-8,15H

4-Chloro-4'-hydroxybenzophenone - Physico-chemical Properties

Molecular Formula	C13H9ClO2
Molar Mass	232.66
Density	1.2082 (rough estimate)
Melting Point	177-181 °C
Boling Point	257 °C (13 mmHg)
Flash Point	100 °C
Solubility	DMSO (Slightly), Methanol (Slightly, Sonicated)
Vapor Presure	4.17E-07mmHg at 25°C
Appearance	White crystal
Color	Pale Beige to Light Brown
BRN	2049956
pKa	7.68±0.15(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.5434 (estimate)
MDL	MFCD00002357
Physical and Chemical Properties	Melting point 177-181°C boiling point 257°C (13 torr) flash point 100°C
Use	As a pharmaceutical fenofibrate Intermediate

4-Chloro-4'-hydroxybenzophenone - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description	S24/25 - Avoid contact with skin and eyes. S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29144000
Hazard Note	Irritant

4-Chloro-4'-hydroxybenzophenone - Reference Information

NIST chemical information	Information provided by: webbook.nist.gov (external link)
use	The impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A- I holmium ediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Bin ding cassette transporter A1 gene in a liver X receptor holmium back ependent manner. used as pharmaceutical fenofibrate intermediate
Production method	1. The reaction method of p-chlorobenzoyl chloride and anisole? ??? After the reaction of p-chlorobenzoyl chloride and anisole, it is prepared by hydrolysis and demethylation. 2. reaction method between p-chlorobenzoyl chloride and phenol????? Dissolve 9.4g(0.1mol) of phenol in 4ml of 10% sodium hydroxide solution, add 14ml(0.110mol) of p-chlorobenzoyl chloride dropwise at 40~45 ℃, add it within 30min, and react at the same temperature for 1h. Cool to room temperature, filter and dry to obtain 22.3g of phenyl p-chlorobenzoate. The yield is 96%, and the melting point is 99~101 ℃.

Last Update：2024-04-09 15:16:50

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4-Chloro-4'-hydroxybenzophenone

4-Chloro-4'-hydroxybenzophenone

4-Chloro-4'-hydroxybenzophenone

CAS: 42019-78-3

Molecular Formula: C13H9ClO2

4-Chloro-4'-hydroxybenzophenone - Names and Identifiers

4-Chloro-4'-hydroxybenzophenone - Physico-chemical Properties

4-Chloro-4'-hydroxybenzophenone - Risk and Safety

4-Chloro-4'-hydroxybenzophenone - Reference Information

Supplier List

4-Chloro-4'-hydroxybenzophenone Request for Quotation

4-Chloro-4'-hydroxybenzophenone

CAS: 42019-78-3

Molecular Formula: C13H9ClO2

4-Chloro-4'-hydroxybenzophenone - Names and Identifiers

4-Chloro-4'-hydroxybenzophenone - Physico-chemical Properties

4-Chloro-4'-hydroxybenzophenone - Risk and Safety

4-Chloro-4'-hydroxybenzophenone - Reference Information

Supplier List

4-Chloro-4'-hydroxybenzophenone